BP103T Pharmaceutics I Theory

Pharmaceutics I syllabus PCI Syllabus

BP103T. Pharmaceutics I Theory syllabus

UNIT I

Historical background and development of profession of pharmacy

History of the profession of Pharmacy in India in relation to pharmacy education, industry, and organization,
Pharmacy as a career,
Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.

Dosage forms

Introduction to dosage forms, classification, and definitions

Prescription

Definition, Parts of prescription, handling of Prescription, and Errors in prescription.

Posology

Definition, Factors affecting posology. Pediatric dose calculations are based on age, body weight, and body surface area.

UNIT II

Pharmaceutical calculations

Weights and measures – Imperial & Metric
the system, Calculations involving percentage solutions, allegation, proof spirit, and isotonic solutions based on freezing point and molecular weight.

Powders

Definition, classification, advantages, and disadvantages,
Simple & compound powders – official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.

Liquid dosage forms

Advantages and disadvantages of liquid dosage forms.
Excipients used in the formulation of liquid dosage forms. Solubility enhancement techniques

UNIT III

Monophasic liquids

Definitions and preparations of Gargles, Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments, and Lotions.

Biphasic liquids
Suspensions

Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and Deflocculated suspension & stability
problems and methods to overcome.

Emulsions

Definition, classification, emulsifying agent, test for the identification of the type of Emulsion, Methods of preparation & stability problems, and methods to overcome.

UNIT IV

Suppositories

Definition, Types, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories.

Pharmaceutical incompatibilities

Definition, classification, physical, chemical, and therapeutic incompatibilities with examples.

UNIT V

Semisolid dosage forms

Definitions, classification, mechanisms, and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams, and gels. Excipients used in semi-solid dosage forms. Evaluation of semi-solid dosages forms

Recommended Books BP103T Pharmaceutics I Theory: (Latest Editions)

  1. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott
    Williams andWalkins, New Delhi.
  2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS publishers,
    New Delhi.
  3. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone,
    Edinburgh.
  4. Indian pharmacopoeia.
  5. British pharmacopoeia.
  6. Lachmann. Theory and Practice of Industrial Pharmacy,Lea& Febiger Publisher, The
    University of Michigan.
  7. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott
    Williams, New Delhi.
  8. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
  9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society,
    Elsevier Health Sciences, USA.
  10. Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC,
    New York.
  11. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker,
    INC, New York.
  12. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and
    Suspensions, Marcel Dekker, INC, New York.

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