BP 304 T. PHARMACEUTICAL ENGINEERING Theory

Pharmaceutical Engineering Syllabus

Pharmaceutical Engineering

UNIT-I

Flow of fluids

Introduction ( Video lecture: Click here )

Types of manometers (Video lecture: Click here)

Reynolds number and its significance (Video lecture: click here)

Bernoulli’s theorem and its applications (Video lecture: Click here)

Energy losses,

Orifice meter,

Venturimeter,

Pitot tube

Rotometer.


Size Reduction

Objectives,

Mechanism size-reduction (Video lecture: Click here)

Laws governing size-reduction (Video lecture: Click here)

Factors affecting size-reduction (Video lecture: Click here)

Principles, construction, working, uses, merits, and demerits of

Hammer mill (Video lecture: Click here)

Ball mill (Video lecture: Click here)

Fluid energy mill (Video lecture: Click here)

Edge runner mill (Video lecture: Click here)

End runner mill (Video lecture: Click here)


Size Separation

Objectives,

applications & mechanism of size separation,

official standards of powders, sieves, size separation

Principles, construction, working, uses, merits, and demerits of

Sieve shaker,

cyclone separator,

Air separator,

Bag filter &

elutriation tank.

UNIT-II

Heat Transfer

Objectives,

applications & Heat transfer mechanisms.

Fourier’s law,

Heat transfer by conduction,

convection & radiation.

Heat interchangers & heat exchangers.

Evaporation

Objectives,

applications and factors influencing evaporation,

differences between evaporation and other heat processes.

Principles, construction, working, uses, merits, and demerits of

Steam jacketed kettle,

horizontal tube evaporator,

climbing film evaporator,

forced circulation evaporator,

multiple-effect evaporator &

The economy of the multiple-effect evaporator.


Distillation

Basic Principles and methodology of

simple distillation,

flash distillation,

fractional distillation,

distillation under reduced pressure,

steam distillation &

molecular distillation

UNIT- III

Drying

Objectives,

applications & mechanism of the drying process,

measurements & applications of Equilibrium Moisture content,

Rate of drying curve.

(Construction of drying Curve Starch and calcium carbonate Video lecture: Click here)

Principles, construction, working, uses, merits, and demerits of

Tray dryer,

drum dryer spray dryer,

fluidized bed dryer,

vacuum dryer,

freeze dryer.

Mixing

Objectives,

applications & factors affecting mixing,

Difference between solid and liquid mixing,

mechanism of solid mixing, liquids mixing and semisolids mixing.

Principles, Construction, Working, uses, Merits and Demerits of

Double cone blender,

twin shell blender,

ribbon blender,

Sigma blade mixer,

planetary mixers,

Propellers,

Turbines,

Paddles &

Silverson Emulsifier

UNIT-IV

Filtration

Objectives,

applications, Theories & Factors influencing filtration, filter aids, filter media.

Principle, Construction, Working, Uses, Merits, and demerits of

Plate & frame filter,

Filter leaf,

rotary drum filter,

Meta filter &

Cartridge filter,

membrane filters and

Seitz filter.


Centrifugation

Objectives,

principle & applications of Centrifugation,

Principles, construction, working, uses, merits and demerits of

Perforated basket centrifuge,

Non-perforated basket centrifuge,

semi continuous centrifuge &

super centrifuge.

UNIT- V

Materials of pharmaceutical plant construction

Corrosion and its prevention:

Factors affecting materials selected for Pharmaceutical plant construction,

Theories of corrosion,

types of corrosion and their prevention.

Ferrous and nonferrous metals,

inorganic and organic non-metals,

basic material handling systems.

Pharmaceutical Engineering Recommended Books: (Latest Editions)

  1. Introduction to chemical engineering – Walter L Badger & Julius Banchero, Latest
    edition.
  2. Solid phase extraction, Principles, techniques and applications by Nigel J.K. Simpson-
    Latest edition.
  3. Unit operation of chemical engineering – Mcabe Smith, Latest edition.
  4. Pharmaceutical engineering principles and practices – C.V.S Subrahmanyam et al., Latest
    edition.
  5. Remington practice of pharmacy- Martin, Latest edition.
  6. Theory and practice of industrial pharmacy by Lachmann., Latest edition.
  7. Physical pharmaceutics- C.V.S Subrahmanyam et al., Latest edition.
  8. Cooper and Gunn’s Tutorial pharmacy, S.J. Carter, Latest edition.

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Second Year B Pharm

Semester III

Theory

BP301T Pharmaceutical Organic Chemistry II – Theory : Click here for Detailed syllabus
BP302T Physical Pharmaceutics I –Theory : Click here for Detailed syllabus
BP303T Pharmaceutical Microbiology – Theory : Click here for Detailed syllabus
BP304T Pharmaceutical Engineering – Theory : Click here for Detailed syllabus

Practical

BP305P Pharmaceutical Organic Chemistry II – Practical : Click here for Detailed syllabus
BP306P Physical Pharmaceutics I – Practical : Click here for Detailed syllabus
BP307P Pharmaceutical Microbiology – Practical : Click here for Detailed syllabus
BP308P Pharmaceutical Engineering – Practical : Click here for Detailed syllabus