Pharmaceutical Microbiology Theory syllabus
Unit I Introduction
Physical parameters for growth, Growth curve (MCQ Video Link: Click here)
Isolation of pure cultures (MCQ Video Link: Click here)
Preservation methods for bacteria
Cultivation of anaerobes,
Quantitative measurement of bacterial growth (total & viable count).
Identification of bacteria using staining techniques (simple, Gram’s &Acid fast staining) and
Biochemical tests (IMViC).
Study of principle, procedure, merits, demerits, and applications of physical, chemical gaseous, radiation, and mechanical method of sterilization.
(MCQ Video Link: Sterilisation Part I, Sterilisation Part II)
Evaluation of the efficiency of sterilization methods.
Equipment employed in large-scale sterilization.
Study of morphology, classification, reproduction/replication, and cultivation of Fungi and Viruses.
Classification and mode of action of disinfectants
Factors influencing disinfection, antiseptics, and their evaluation.
For bacteriostatic and bactericidal actions: Evaluation of bactericidal & Bacteriostatic.
Sterility testing of products (solids, liquids, ophthalmic, and other sterile products) according to IP, BP, and USP.
Designing of aseptic area, laminar flow equipment;
study of different sources of contamination in an aseptic area and methods of prevention, clean area classification.
Principles and methods of the different microbiological assay.
Methods for standardization of antibiotics, vitamins, and amino acids.
Assessment of a new antibiotic.
Types of spoilage,
Factors affecting the microbial spoilage of pharmaceutical products, sources, and
Types of microbial contaminants,
Assessment of microbial contamination and spoilage.
Preservation of pharmaceutical products using antimicrobial agents,
Evaluation of microbial stability of formulations.
Growth of animal cells in culture, the general procedure for cell culture,
Primary, established and transformed cell cultures.
Application of cell cultures in pharmaceutical industry and research.
Pharmaceutical Microbiology Recommended Books (Latest Edition)
- W.B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific
publications, Oxford London.
- Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors,
- Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
- Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.
- Rose: Industrial Microbiology.
- Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
- Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.
- Peppler: Microbial Technology.
- I.P., B.P., U.S.P.- latest editions.
- Ananthnarayan : Text Book of Microbiology, Orient-Longman, Chennai
- Edward: Fundamentals of Microbiology.
- N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
- Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company
- Second Year B Pharm
- Semester III
- BP301T Pharmaceutical Organic Chemistry II – Theory : Click here for Detailed syllabus
- BP302T PhysicalPharmaceuticsI –Theory : Click here for Detailed syllabus
- BP303T Pharmaceutical Microbiology – Theory : Click here for Detailed syllabus
- BP304T Pharmaceutical Engineering – Theory : Click here for Detailed syllabus
- BP305P Pharmaceutical Organic Chemistry II – Practical : Click here for Detailed syllabus
- BP306P Physical Pharmaceutics I – Practical : Click here for Detailed syllabus
- BP307P Pharmaceutical Microbiology – Practical : Click here for Detailed syllabus
- BP308P Pharmaceutical Engineering – Practical : Click here for Detailed syllabus
- Semester IV
- BP401T Pharmaceutical Organic Chemistry III– Theory : Click here for Detailed syllabus
- BP402T Medicinal Chemistry I – Theory : Click here for Detailed syllabus
- BP403T Physical Pharmaceutics II – Theory : Click here for Detailed syllabus
- BP404T Pharmacology I – Theory : Click here for Detailed syllabus
- BP405T Pharmacognosy I – Theory : Click here for Detailed syllabus
- Semester III