February 19, 2025

Microbiological assay, test, and aseptic area MCQ with answers

Microbiological assay, test, and aseptic area MCQ with answers

Mixing and storage of the compounded preparations should be done ______the aseptic area.
Inside
Outside
Beside
Near 

Answer: Outside

The full form of HEPA filter is?
High-efficiency particulate air
High effective particulate air 
High effective particles in the air
High efficiency of particles in air

Answer: High-efficiency particulate air

Laminar airflow unites use _____ filters.
Candle
Millipore
Seitz
HEPA

Answer: HEPA

The minimum effective flowrate of air in a laminar flow hood is  _____
Not less than 100 cubic feet/minute
Not less than 1000 cubic feet/minute
Not less than 1500 cubic feet/minute
Not less than 1100 cubic feet/minute

Answer: Not less than 100 cubic feet/minute

In the cup plate method, the graph plotted relates ______to the logarithm of the concentration of antibiotics.
Time 
Density
zone diameter
antibacterial capacity

Answer: zone diameter

The cup plate method depends on the _______of antibiotics from a cavity through the solidified agar layer in a Petri plate.
Diffusion
Dissolution 
Dispersion 
Dissociation

Answer: Diffusion

The growth of test microorganisms is inhibited entirely in a circular area or zone around the cavity or cylinder containing a solution of antibiotic is called______.
Concentration of Inhibition  
Capacity of Inhibition 
Zone of Inhibition
Ratio of Inhibition

Answer: Zone of Inhibition

The lowest concentration of antimicrobial found to inhibit the growth of a particular test microorganism is known as ______
Minimum Inhibitory Concentration
Maximum Inhibitory Concentration 
Median Inhibitory Concentration
Mean Inhibitory concentration

Answer: Minimum Inhibitory Concentration

______ is a well-defined area where the production of sterile preparation should be carried out.
Compounding area
Manufacturing area
Aseptic area
Quarantine area

Answer: Aseptic area

Parenteral preparations are prepared in _______ area.
Class A
Class B
Class C
Class D 

Answer: Class A

Positive air pressure means airflow from __________
High-pressure area to low-pressure area
Low-pressure area to high-pressure area
Similar pressure on both side
Steady pressure

Answer: High-pressure area to low-pressure area

Microbiological assay of vitamins can be performed by
Only titrimetric method
Only turbidimetric method
Both Titrimetric and turbidimetric methods
Agar plate method

Answer: Both Titrimetric and turbidimetric methods

 _______is for handling of components after washing 
Class A
Class B
Class C
Class D

Answer: Class D

Laminar airflow allows  ________movement of air.
Unidirectional
Nonunidirectional
Combined
Multidirectional

Answer: Unidirectional

The air filtered from the laminar airflow is claimed to be free from the microbial contamination
75%
100%
50%
99.97%

Answer: 99.97%

Sink and drain should be excluded from _____zone
Class A and B
Class B and D
Class A and D
Class C

Answer: Class A and B

_________types of materials are used for  construction of floors.
Polythene
Glass
Quartz 
Flexing and non-flexing

Answer: Flexing and non-flexing

Assessment of new antibiotics can be done by figuring out their________
Minimum Inhibitory Concentration
Maximum Inhibitory Concentration 
Mean Inhibitory Concentration
Antibacterial properties

Answer: Minimum Inhibitory Concentration

_______  assay method is not recommended for turbid or cloudy preparation.
Turbidimetric
Titrimethod
Tube dilution
Cup plate

Answer: Turbidimetric

Repackaging of products purchased in bulk into smaller containers. 
Maintains product sterility
Increased handling of the product inevitably increases the risk of contamination
Reduces risk of contamination
Reduces product quantity

Answer: Increased handling of the product inevitably increases the risk of contamination

Following are the sources of contamination  in the parenteral preparation except 
Water
Containers
Air
Sterile Water for Injection

Answer: Sterile Water for Injection

The compounded preparations are transferred to the aseptic area through ______where the filling operation is carried out.
Personal 
Pipelines
Containers
Open trays

Answer: Pipelines

The microbiological assay of vitamins and amino acids includes _____
The ability of test microorganisms to synthesize the factor
Killing of microorganisms
The extent to kill microorganisms
Microbial resistance

Answer: The ability of test microorganisms to synthesize the factor

______ Class is background room conditions for activities requiring grade A.
Class C
Class D
Class B
Class E

Answer: Class B

Vitamin B12 can be estimated and determined by using organism
Lactobacillus sps
Lactobacillus leichmanni
Bacillus subtilis
E.Coli

Answer: Lactobacillus leichmanni

Negative control in the liquid dilution method is used for checking ________ of media.
Compatibility 
Sterility
Concentration 
Effect

Answer: Sterility


Microbiology MCQ with answers:


Suggested readings:

Recommended readings:

Second Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

S Y B Pharm Sem IIIS Y B Pharm Sem IV
BP301T Pharmaceutical Organic Chemistry II TheoryBP401T Pharmaceutical Organic Chemistry III Theory
BP302T Physical Pharmaceutics I TheoryBP402T Medicinal Chemistry I Theory
BP303T Pharmaceutical Microbiology TheoBP403T Physical Pharmaceutics II Theory
BP304T Pharmaceutical Engineering TheoryBP404T Pharmacology I Theory
BP305P Pharmaceutical Organic Chemistry II PracticalBP405T Pharmacognosy I Theory
BP306P Physical Pharmaceutics I PracticalBP406P Medicinal Chemistry I Practical
BP307P Pharmaceutical Microbiology PracticalBP407P Physical Pharmaceutics II Practical
BP308P Pharmaceutical Engineering PracticalBP408P Pharmacology I Practical
BP409P Pharmacognosy I Practical

MCQ:

BP302T Physical Pharmaceutics I Theory MCQ

BP304T Pharmaceutical Engineering Theory MCQ

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