July 19, 2024

Suppositories, Pharmaceutical incompatibilities MCQ with answers

Suppositories, Pharmaceutical incompatibilities MCQ with answers

One of the following is disadvantage of cocoa butter suppository base
Solid at room temperature but melts in body
Polymorphism
Miscibility with many ingredients
Blandness

Answer: Polymorphism

Interaction between two or more substances that may lead to a change in colour, odour, taste, viscosity and morphology is termed as _________.
Biological incompatibility
Physical incompatibility
Therapeutic incompatibility
Chemical incompatibility

Answer: Physical incompatibility

Phase inversion is observed when emulsion prepared by using soaps of monovalent cation is mixed with polyvalent cations.This is example of __________ incompatibility.
Chemical
Physical
Therapeutic
Biological

Answer: Chemical

Witepsol is classified as which type of suppository base?
Glycero-Gelatin base
Synthetic base
Cocoa butter base
Macrogol base

Answer: Synthetic base

Double decomposition is an example of _____________ incompatibility.
Chemical
Physical
Therapeutic
Biological

Answer: Chemical

Which form of cocoa butter is considered to be stable for suppository?
Alpha Crystal
Gamma Crystals
Delta Crystals
Beta Crystal

Answer: Beta Crystal

________ is a remedy to overcome the incompatibility between oil and water.
Addition of sweetner
Addition of surfactant
Addition of preservative
Mixing of two phases by stirring

Answer: Addition of surfactant

__________ measures the time required by suppository to soften under pressures similar to those found in the rectum in the presence of water at 37◦C.
Solidification test
Disintegration test
Liquefaction test
Dissolution test

Answer: Liquefaction test

Urethral suppositories also called as _________
Pessaries
Bougies
Enema
Douches

Answer: Bougies

Suppositories can be prepared by _________.
Precipitation method
Redispersion Method
Maceration method
Compression moulding

Answer: Compression moulding

When water is added to tincture containing resinous matter, resin agglomerates are formed. This is example of __________ incompatibility.
Chemical
Physical
Therapeutic
Biological

Answer: Physical

Displacement values calculation ensures ________.
Correct amount of base
Correct amount of drug
Formation of stable suppositories
Formation of easily mouldable suppositories.

Answer: Correct amount of drug


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