Effervescent Granules Pharmaceutics Lab
Effervescent Granules covered in Pharmaceutics lab. Effervescent Granules are prepared by various methods. Various effervescent granules example are available in the market with numerous effervescent granules brand name. effervescent granules preparation should be prepared with care
Aim:
Preparation and evaluation of Effervescent Granules
Glasswares:
Tile, glass rod, & Wide mouth container
Formula:
| Ingredients | Quantity Given | Activity |
| Sodium sulphate | 200 mg | Saline laxative |
| Citric acid monohydrate | 210 mg | Effervescent mixture |
| Tartaric acid | 240 mg | Effervescent mixture |
| Sodium bicarbonate | 500 mg | Effervescent mixture |
Procedure:
Time needed: 1 hour
How to prepare effervescent granules?
- Sieve the powder
The powder was sifted through sieve no. 60
- Mix the powder
Mixed and transferred to a hot porcelain dish
- Heating
The mixture was heated on a boiling water bath without stirring or pressing the powder.
- Sieve through Sieve no 8
The resultant mixture was sieved through sieve no. 8.
- Dry the granules
Granules were dried at 40˚C.
- Use of Sieve number 14 and 20
Dried granules were passed through sieve no 14 and retained over sieve no 20.
- Fill in the container
The product was packed in a wide-mouth container.
Effervescent granules preparation Precautions:
1. Weigh 15% extra quantity.
2. Heat porcelain dish before using.
3. Do not over-dry the granules.
Theory :
The mixture of citric acid and tartaric acid with sodium bicarbonate. Usually, a medicament is included and saccharin or sucrose may be added as a sweetening agent. When the patient dissolves the dose in water, the acids and bicarbonates react together producing carbonic acids, and preparation is taken during effervescence or immediately afterwards.
Reaction:
H8C6O7.H2O + 3NaHCO3 → Na3C6H5O7 + 4H2O + 3CO2
Citric acid Sod. Bicarbonate Sodium Citrate
Container / Storage:
Store in a cool and dry place
Category :
Laxative
Labeling directions:
Add 1 teaspoonful in a glassful of water and take during the evolution of CO2 gas.
Organoleptic Evaluation:
| Sr. No | Property Evaluated | Observation |
effervescent granules example
Examples of such acids include tartaric acid and citric acid.
effervescent granules example of bases include sodium carbonate, potassium bicarbonate, sodium bicarbonate.
They are usually prepared from a combination of citric and tartaric acid rather than from a single acid because the use of either acid alone causes difficulties. When tartaric acid is the sole acid, the resulting granules readily crumble and lack mechanical strength. Citric acid alone results in a sticky mixture which is difficult to granulate during the manufacturing process.
effervescent granules brand name
effervescent granules brand name include Avosoda Granules, Renalka Granules, Ural granules, Utix Granules
effervescent granules ppt
effervescent granules ppt are available on pharmacyinfoline youtube channel description. effervescent granules ppt include Preparation, precautions and calculations
Video Leture
Pharmaceutics Practical
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
Ural granules
Vaccinium macrocarpon (Cranberry) fruit juice dry 368.3 mg, equiv. fresh juice 9.2 g. Also contains: sodium bicarbonate 1.75 g, tartaric acid 500 mg, citric acid anhydrous 714 mg, sodium citrate anhydrous 625 mg, silica colloidal anhydrous 10 mg, saccharin sodium 8 mg, magnesium hydroxide 23.8 mg, calcium phosphate 4 mg.
Utix granules
It is indicated to relieve the burning discomfort and frequency caused by mild urinary tract infections such as cystitis, pyelonephritis, urethritis; and to reduce the formation of uric acid and cystine calculi in chronic gout. It may enhance the action of certain antibiotics such as Sulphonamide and relieve symptoms associated with gastric hyperacidity.
renalka effervescent granules
Renalka Granules is available in the following packages and strengths Renalka Granules – Packages: 4g Sachet x 28, 4g Sachet x 6
