Sulphur ointment preparation Simple ointment Pharmaceutics Lab
How to prepare Sulphur ointment?
Aim:
Preparation and Evaluation of Sulphur ointment
Requirement:
Glass slab, spatula, wide-mouth glass bottle etc.
Formula:
| Ingredients | Quantity Given | Activity |
| Sublimed Sulphur | 10 gm | Scabicide |
| Simple Ointment White | 90 gm | Ointment Base |
Procedure:
Time needed: 1 hour
How to prepare Sulphur ointment?
- Sieving
Sulphur was passed through sieve no 85.
- Weighing
Weigh the sieved Sulphur as per the working formula
- Trituration
Sulphur was triturated with a portion of simple ointment until smooth.
- Mixing with Simple ointment
Gradually add the remaining quantity and mixed thoroughly.
- Filling in container
Fill the smooth ointment in a wide mouth container or collapsible tube
Theory:
Sulphur is an insoluble solid incorporated in simple ointment by trituration method. Sulphur is used as anti-bacterial. Sulphur ointment is also used to treat various skin disorders like seborrheic dermatitis, scabies etc. Simple ointment is used as ointment base in this formulation.
Category:
It acts as a Scabicide
Storage:
Store in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Dose:
Use the 5 to 10% ointment one or two times a day. Use as required.
Direction:
Do not apply on broken skin and near the eye.
Precautions:
Avoid getting this medicine in your eyes, nose, mouth, or on your lips. O Rinse with water if contact does occur.
Do not use on open wounds or on sunburned, windburned, dry or irritated skin.
Keep away from children.
Definitions:
- Anti-bacterial agent: Anti-bacterial is an agent that interferes with the growth and reproduction of bacteria. These agents kill or prevent bacteria.
- Ointment Base: The ointment base is a substance or a part of ointment which serves as carrier or vehicle for the medicament.
Hard paraffin & soft paraffin are hydrocarbon bases. They form an occlusive film on the skin, absorb less water but are stable to heat and resist rancidification and microbial growth. Wool fat is an anhydrous type of absorptive base that absorbs twice its weight of water to produce W/O emulsion. Long-chain alcohols like Cetostearyl alcohols are used in combination with other bases to improve emollient and water absorption capacity or as well as W/O emulsion stabilizer.
Ingredients and quantity is as Wool fat 50 gm, Hard paraffin 50 gm, Cetostearyl alcohol 50 gm, and White soft paraffin 850 gm
| Ingredients | Qty Given |
| Wool fat | 50 gm |
| Hard paraffin | 50 gm |
| Cetostearyl alcohol | 50 gm |
| White soft paraffin | 850 gm |
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