Oral Rehydration Salt Pharmaceutics I Practical
Aim:
Preparation and evaluation of Oral Rehydration Salt
Requirement:
Tile, glass rod, & Wide mouth container
Formula:
Ingredients | Quantity Given | Activity |
Sodium chloride | 2.6 gm | Sodium and potassium are needed to replace the body losses of these essential ions during diarrhoea (and vomiting) |
Glucose, anhydrous | 13.5 gm | Glucose facilitates the absorption of sodium (and hence water) on a 1:1 molar basis in the small intestine. |
Potassium chloride | 1.5 gm | |
Trisodium citrate hydrate | 2.9 gm | Citrate corrects the acidosis that occurs as a result of diarrhoea and dehydration |
Procedure:
The ingredients were weighed and mixed in geometric proportion on a clean and dry tile.
The powder was filled in a wide mouth glass container.
Category:
Electrolyte and fluid replenisher.
Storage:
Store in a cool and dry place
Labelling Directions:
Dissolve the contents of the packet in 1litre of freshly boiled and cooled water.
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