Carbopol Gel Pharmaceutics I Practical

Carbopol Gel Pharmaceutics I Practical

Aim: Preparation and Evaluation of Carbopol Gel

Glassware’s: Beaker, glass rod, collapsible aluminium tube etc. Formula:

Ingredients	Qty given	Qty taken
Propylene glycol	20g		Humectant
Carbopol 934	1g		Gelling polymer
Triethanolamine	q.s. pH 7		pH adjuster
Purified water	q.s. to 100		Vehicle

Procedure: Carbopol was soaked in 3/4th quantity of water and kept aside for 30 mins. Then propylene glycol was added and pH adjusted up to 7 with triethanolamine. The gel was filled in collapsible aluminium tubes.

Theory: Carbopol is a synthetic polyacrylic acid with ionizable carboxyl groups. It swells when dispersed in water and hydration helps in the uncoiling of the polymeric chain. In presence of alkali, carboxylate anions (COO‾) are generated on the backbone of the polymeric chain which repels from each other and these repulsive forces further help in the extension of polymeric chains. Thus it gives higher viscosity in presence of alkaline pH 7-8

Category: Non medicated gel

Labelling direction: For External Use Only. Keep in a cool and dry place. Do not freeze.

Storage: Store in a cool dry place.

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Pharmaceutics Practical

Syrup IP’66	Liquid paraffin emulsion
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Paracetamol pediatric elixir	Dusting powder
Terpin Hydrate Linctus IP’66	Divided powders
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Cresol with soap solution	Zinc Oxide suppository
Aqueous Iodine Solution	Sulphur ointment
Calamine lotion	Non-staining-iodine ointment
Magnesium Hydroxide mixture	Carbopal gel
Aluminium hydroxide gel	Iodine gargle
Turpentine Liniment	Chlorhexidine mouthwash

First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-I	F Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I Theory	BP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I Theory	BP202T Pharmaceutical Organic Chemistry I Theory
BP103T Pharmaceutics I Theory	BP203T Biochemistry – Theory
BP104T Pharmaceutical Inorganic Chemistry Theory	BP204T Pathophysiology – Theory
BP105T Communication skills Theory	BP205T Computer Applications in Pharmacy Theory
BP106RBT Remedial Biology	BP206T Environmental sciences – Theory
BP106RMT Remedial Mathematics Theory	BP207P Human Anatomy and Physiology II Practical
BP107P Human Anatomy and Physiology Practical	BP208P Pharmaceutical Organic Chemistry I Practical
BP108P Pharmaceutical Analysis I Practical	BP209P Biochemistry Practical
BP109P Pharmaceutics I Practical	BP210P Computer Applications in Pharmacy Practical
BP110P Pharmaceutical Inorganic Chemistry Practical
BP111P Communication skills Practical
BP112RBP Remedial Biology Practical

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Suggested readings:

• 109P Pharmaceutics I Practical, Lab Manual PDF, Downloads
• Aluminium Hydroxide Gel Pharmaceutics I Practical
• Sodium Alginate Gel Pharmaceutics Lab Practical Manual PDF
• Ointment, Paste, Cream, Gels MCQ with answer
• Preparation of buffer solution and measurement of pH

Recommended readings:

• Sodium Alginate Gel

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