Strong solution of ammonium acetate
Aim: Preparation and Evaluation of Strong solution of ammonium acetate
Glassware’s: Beaker, glass rod, & wide mouth amber coloured bottle
|Glacial acetic acid||453 g||In situ ammonium acetate formation.|
|Ammonium bicarbonate||470 g|
|Ammonium solution strong||100 ml or q.s||Neutralizing agent|
|Purified Water||q.s to 1000 ml|
Glacial acetic acid, ammonium bicarbonate was mixed in 350 ml of purified water.
Strong ammonia solution was added to the above solution until a drop of resulting solution when added to10 drops of water and one drop of bromothymol blue gave a full blue colour and one drop tested with to10 drops of water and one drop of thymol blue gave a full yellow colour.
The solution was diluted with water to make up the volume.
The solution was filled in a lead-free glass container.
Ammonium acetate is prepared in situ by a chemical reaction.
NH4 H CO3 +CH3 COOH CH3 COONH4 + CO2 + H2O
Excess acid is added which is not completely neutralized, dilute solutions are used to give a faster reaction to obtain the solution of desired strength. Ammonia is added to obtain a condition of complete neutralization. (pH 7 to 8).
Category: Mild expectorant, diaphoretic and diuretic Dose: 1 to 5 ml.
Storage: Store in a cool, dry place.
Labelling direction: Ammonium acetate 55 to 60 % W/V
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