September 30, 2023

Strong solution of ammonium acetate

Strong solution of ammonium acetate

Aim: Preparation and Evaluation of Strong solution of ammonium acetate

Glassware’s: Beaker, glass rod, & wide mouth amber coloured bottle


IngredientsQty givenActivity
Glacial acetic acid453 gIn situ ammonium acetate formation.
Ammonium bicarbonate470 g
Ammonium solution strong100 ml or q.sNeutralizing agent
Purified Waterq.s to 1000 ml 


Glacial acetic acid, ammonium bicarbonate was mixed in 350 ml of purified water.

Strong ammonia solution was added to the above solution until a drop of resulting solution when added to10 drops of water and one drop of bromothymol blue gave a full blue colour and one drop tested with to10 drops of water and one drop of thymol blue gave a full yellow colour.

The solution was diluted with water to make up the volume.

The solution was filled in a lead-free glass container.


Ammonium acetate is prepared in situ by a chemical reaction.

NH4 H CO3 +CH3 COOH                   CH3 COONH4   + CO2   +    H2O

Excess acid is added which is not completely neutralized, dilute solutions are used to give a faster reaction to obtain the solution of desired strength. Ammonia is added to obtain a condition of complete neutralization. (pH 7 to 8).

Category: Mild expectorant, diaphoretic and diuretic Dose: 1 to 5 ml.

Storage: Store in a cool, dry place.

Labelling direction: Ammonium acetate 55 to 60 % W/V

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First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-IF Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I TheoryBP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I TheoryBP202T Pharmaceutical Organic Chemistry I Theory
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BP108P Pharmaceutical Analysis I PracticalBP209P Biochemistry Practical
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