Strong solution of ammonium acetate

Formula:

IngredientsQty givenQty takenActivity
Glacial acetic acid453 gIn situ ammonium acetate formation.
Ammonium  bicarbonate470 g
Ammonium solution strong100 ml or q.sNeutralizing agent
Purified Waterq.s to 1000 ml

Procedure:

Glacial acetic acid, ammonium bicarbonate was mixed in 350 ml of purified water.

Strong ammonia solution was added to the above solution until a drop of resulting solution when added to 10 drops of water  and one drop of bromothymol blue gave a full blue colour and one drop tested with to 10 drops of water   and one drop of thymol blue gave a full yellow colour.

The solution was diluted with water to make up the volume. Solution was filled in lead free glass container.

Category:

Mild expectorant, diaphoretic and diuretic

 Dose:

1 to 5 ml.

Storage:

Store in cool, dry place.

Labeling Direction:

Ammonium acetate 55 to 60 % W/V

Theory:

Ammonium acetate is prepared in situ by a chemical reaction.

NH4 H CO3  +CH3 COOH                   CH3 COONH4  + CO2   +     H2O

 Excess acid is added which is not completely neutralized, dilute solutions are used to give a faster reaction to obtain solution of desired strength. Ammonia is added to obtain a condition of complete neutralization. (pH 7 to 8).      

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