Calamine lotion: Design the formula for calamine lotion
Calamine lotion Formula:
| Ingredients | Qty Given | Qty Taken | Activity |
| Calamine | 150 gm | Protectant | |
| Zinc oxide | 50 gm | ||
| Bentonite | 30 gm | Flocculating agent | |
| Sodium citrate | 5 gm | Deflocculating agent | |
| Liquefied phenol | 5 ml | preservative | |
| Glycerin | 50 ml | emollient | |
| Purified water freshly boiled and cooled | q.s to 1000 ml | Vehicle |
Procedure:
Calamine, zinc oxide and bentonite were triturated with a solution of sodium citrate.
Liquefied phenol, glycerine and sufficient purified water were added to produce 1000 ml.
Calamine lotion Theory:
Calamine is zinc oxide with a small amount of ferric oxide. Both are indiffusible solids, so bentonite is added as a thickening agent which causes flocculation of calamine. However, the preparation becomes viscous and is difficult to pour from the bottle. Sodium citrate is added to cause partial deflocculation of calamine and makes the preparation pourable. Liquefied phenol is used as a preservative and glycerol is used as an emollient.
Calamine lotion Category:
Topical Protective
Container & storage:
Well closed container, Keep away from light.
Labelling direction:
For External Use Only.
Apply to skin as required and allow to dry.
Shake well before use.
Frequently asked question on Calamine lotion formula/ preparation
Calamine lotion works in several ways:
Astringent effect: Calamine and zinc oxide help to dry out minor surface irritations, reducing the urge to scratch.
Cooling sensation: The evaporation of the lotion from the skin creates a cooling effect, which can numb itching and provide temporary relief.
Anti-inflammatory effect: Calamine and zinc oxide may have mild anti-inflammatory properties that help reduce swelling and redness.
Protective barrier: Zinc oxide forms a physical barrier on the skin, protecting it from further irritation and promoting healing.
Calamine lotion is best for relieving mild itching and discomfort associated with:
Sunburn
Insect bites and stings
Minor skin rashes and allergies
Poison ivy and oak
Chickenpox
Eczema (mild cases)
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