
UNIT I
Impurities in pharmaceutical substances
Sources and types of impurities
Limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate
General methods of preparation, assay for the compounds superscripted with an asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classesUNIT II
Acids, Bases and Buffers
Buffer equations and buffer capacity in general,
Buffers in pharmaceutical systems,
Preparation and stability of buffers,
Buffered isotonic solutions,
Measurements of tonicity,
Calculations and methods of adjusting isotonicity.
Major extra and intracellular electrolytes
Functions of major physiological ions,
Electrolytes used in the replacement therapy: Sodium chloride, Potassium chloride, Calcium gluconate
Oral Rehydration Salt (ORS),
Physiological acid-base balance.
Dental products
Dentifrices,
The role of fluoride in the treatment of dental caries,
Desensitizing agents,
Calcium carbonate,
Sodium fluoride,
Zinc eugenol cement.
UNIT III
Gastrointestinal agents
Acidifiers
Ammonium chloride*
Dilute Hydrochloric acid (Dil. HCl)
Antacid
Ideal properties of antacids,
Combinations of antacids,
Sodium Bicarbonate*,
Aluminum hydroxide gel,
Magnesium hydroxide mixture
Cathartics
Magnesium sulphate,
Sodium orthophosphate,
Kaolin,
Bentonite
Antimicrobials
The mechanism,
Classification,
Potassium permanganate,
Boric acid,
Hydrogen peroxide,
Chlorinated lime,
Iodine and its preparations
UNIT IV
Miscellaneous compounds
Expectorants
Potassium iodide,
Ammonium chloride*
Emetics
Copper sulphate*,
Sodium potassium tartrate
Haematinics
Ferrous sulphate*,
Ferrous gluconate
Poison and Antidote
Sodium thiosulphate*,
Activated charcoal,
Sodium nitrite
Astringents
Zinc Sulphate,
Potash Alum
UNIT V
Radiopharmaceuticals
Radioactivity,
Measurement of radioactivity,
Properties of α, β, γ radiations,
Half-life,
Radioisotopes and study of radioisotopes:
Sodium iodide: Storage conditions, precautions
Pharmaceutical application of radioactive substances.
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
Suggested readings
Recommended readings
- Pharmaceutics I Practical
- Social Pharmacy Theory
- B Pharmacy PCI Syllabus
- Solubility expression physical pharmaceutics
- Pharmacovigilance Theory
- Pharmaceutical Regulatory Science



