Calcium carbonate: General methods of preparation, assay, properties and medicinal uses
Calcium carbonate is a chemical compound with the formula CaCO3. It is a white, odorless powder that is insoluble in water but soluble in acids. Calcium carbonate occurs naturally in rocks, seashells, and eggshells, and is commonly used in a variety of industrial and medicinal applications. Here is an overview of the general methods of preparation, assay, properties, and medicinal uses of calcium carbonate.
Preparation: Calcium carbonate can be prepared by reacting calcium oxide with carbon dioxide:
CaO + CO2 → CaCO3
It can also be obtained from natural sources, such as limestone, chalk, or marble.
Assay: The assay of calcium carbonate involves measuring the percentage of CaCO3 present in the sample. This can be done by a variety of methods, such as acid-base titration or gravimetric analysis.
Properties: Calcium carbonate has a number of important physical and chemical properties. It is a white, odorless powder that is insoluble in water but soluble in acids. It has a high melting point of 825°C and a density of 2.71 g/cm3. Calcium carbonate is non-toxic and non-flammable, making it a safe and useful compound for a variety of applications.
Medicinal uses: Calcium carbonate is commonly used in the pharmaceutical industry as a calcium supplement to prevent and treat osteoporosis, a condition that weakens bones and makes them more susceptible to fractures. It is also used as an antacid to neutralize stomach acid and relieve symptoms of heartburn, indigestion, and acid reflux. Additionally, calcium carbonate is used in the manufacturing of dietary supplements, toothpaste, and cosmetics.
In summary, calcium carbonate is a versatile compound with a wide range of industrial and medicinal applications. Its properties, including its high melting point and non-toxic nature, make it a useful and safe compound for a variety of applications. Its medicinal uses, as a calcium supplement and antacid, are important for maintaining bone health and managing symptoms of acid reflux and other digestive issues.
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
Suggested readings:
