July 19, 2024

Sodium Bicarbonate: General methods of preparation, assay, properties and medicinal uses

Sodium Bicarbonate: General methods of preparation, assay, properties and medicinal uses

Preparation: Sodium bicarbonate, also known as baking soda, is prepared by the Solvay process, which involves the reaction of sodium chloride, ammonia, carbon dioxide, and water. The process results in the formation of sodium bicarbonate crystals, which are then harvested, washed, and dried.

Assay: The assay of sodium bicarbonate involves the measurement of its alkalinity or its ability to neutralize acid. This is typically done by titrating a solution of sodium bicarbonate with a strong acid, such as hydrochloric acid, and measuring the amount of acid required to neutralize the bicarbonate.

Properties: Sodium bicarbonate is a white crystalline powder that is odorless and has a slightly salty taste. It is highly soluble in water and has a pH of approximately 8.3. Sodium bicarbonate is an alkaline compound that can neutralize acid, making it useful for a variety of medicinal and household purposes.

Medicinal Uses: Sodium bicarbonate has several medicinal uses, including:

  1. Antacid: Sodium bicarbonate can be used as an antacid to relieve symptoms of heartburn, acid reflux, and indigestion. It works by neutralizing excess acid in the stomach.
  2. Treatment of metabolic acidosis: Sodium bicarbonate can be used to treat metabolic acidosis, a condition in which there is too much acid in the body. It works by buffering the excess acid and restoring the body’s pH balance.
  3. Treatment of kidney stones: Sodium bicarbonate can be used to prevent the formation of kidney stones by alkalinizing the urine and reducing the formation of uric acid crystals.
  4. Topical use: Sodium bicarbonate can be used topically as a mild abrasive and antiseptic for skin and oral care.

Overall, sodium bicarbonate is a versatile compound with a variety of medicinal uses. It is generally considered safe when used as directed, although high doses or long-term use can lead to side effects such as nausea, vomiting, and electrolyte imbalances. Patients should always consult with their healthcare provider before using sodium bicarbonate for any medicinal purpose.

First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-IS Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I TheoryBP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I TheoryBP202T Pharmaceutical Organic Chemistry I Theory
BP103T Pharmaceutics I TheoryBP203T Biochemistry – Theory
BP104T Pharmaceutical Inorganic Chemistry TheoryBP204T Pathophysiology – Theory
BP105T Communication skills TheoryBP205T Computer Applications in Pharmacy Theory
BP106RBT Remedial BiologyBP206T Environmental sciences – Theory
BP106RMT Remedial Mathematics TheoryBP207P Human Anatomy and Physiology II Practical
BP107P Human Anatomy and Physiology PracticalBP208P Pharmaceutical Organic Chemistry I Practical
BP108P Pharmaceutical Analysis I PracticalBP209P Biochemistry Practical
BP109P Pharmaceutics I PracticalBP210P Computer Applications in Pharmacy Practical
BP110P Pharmaceutical Inorganic Chemistry Practical
BP111P Communication skills Practical
BP112RBP Remedial Biology Practical

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