February 19, 2025

Aluminum hydroxide gel: General methods of preparation, assay, properties and medicinal uses

Aluminum hydroxide gel: General methods of preparation, assay, properties and medicinal uses

Aluminum hydroxide gel, also known as aluminum trihydroxide, is a white, odorless, and tasteless gel-like substance. It is commonly used as an antacid and in the preparation of vaccines. Here are some general methods of preparation, assay, properties, and medicinal uses of aluminum hydroxide gel:

Preparation: Aluminum hydroxide gel is prepared by reacting aluminum sulfate with sodium hydroxide in water. The resulting gel is then washed, dried, and ground into a fine powder. The gel can also be prepared by precipitation of aluminum salts with an alkali.

Assay: The assay of aluminum hydroxide gel is typically performed by determining the amount of aluminum present in the sample. This can be done using a variety of methods, including atomic absorption spectroscopy, inductively coupled plasma mass spectrometry, and complexometric titration.

Properties: Aluminum hydroxide gel is an amphoteric compound, which means it can act as both an acid and a base. It has a high surface area and adsorption capacity, which makes it an effective adsorbent. The gel is insoluble in water and organic solvents, but it is soluble in strong acids and bases.

Medicinal uses: Aluminum hydroxide gel is commonly used as an antacid to treat symptoms of heartburn, indigestion, and other gastrointestinal disorders. It works by neutralizing stomach acid and reducing the production of digestive enzymes. The gel is also used as an adjuvant in vaccines, where it enhances the immune response by promoting the uptake and presentation of antigens to immune cells.

In addition to its medicinal uses, aluminum hydroxide gel is used in a variety of industrial applications, including as a flame retardant, a filler in plastics and rubber, and a catalyst in chemical reactions.

First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-IS Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I TheoryBP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I TheoryBP202T Pharmaceutical Organic Chemistry I Theory
BP103T Pharmaceutics I TheoryBP203T Biochemistry – Theory
BP104T Pharmaceutical Inorganic Chemistry TheoryBP204T Pathophysiology – Theory
BP105T Communication skills TheoryBP205T Computer Applications in Pharmacy Theory
BP106RBT Remedial BiologyBP206T Environmental sciences – Theory
BP106RMT Remedial Mathematics TheoryBP207P Human Anatomy and Physiology II Practical
BP107P Human Anatomy and Physiology PracticalBP208P Pharmaceutical Organic Chemistry I Practical
BP108P Pharmaceutical Analysis I PracticalBP209P Biochemistry Practical
BP109P Pharmaceutics I PracticalBP210P Computer Applications in Pharmacy Practical
BP110P Pharmaceutical Inorganic Chemistry Practical
BP111P Communication skills Practical
BP112RBP Remedial Biology Practical

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