February 22, 2024

Limit Test of Sulphate Pharmaceutical Analysis I Practical, Lab Manual

Limit Test of Sulphate Pharmaceutical Analysis I Practical, Lab Manual


Pharmaceutical Analysis I Practical: Limit test for (1) Chloride (2) Sulphate (3) Iron (4) Arsenic Preparation and standardisation of (1) Sodium hydroxide (2) Sulphuric acid (3) Sodium thiosulfate (4) Potassium permanganate (5) Ceric ammonium sulphate Assay (1) Ammonium chloride (2) Ferrous sulphate(3) Copper sulphate (4) Calcium gluconate (5) Hydrogen peroxide (6) Sodium benzoate (7) Sodium Chloride Determination of Normality (1) Conductometric titration of strong acid against a strong base (2) Conductometric titration of strong acid and weak acid against a strong base (3) Potentiometric titration


Aim

To observe limit test for Sulphate impurities

Principle

The limit test for sulphate is mainly designed to control sulphate impurity in inorganic substances. It depends upon the precipitation of barium sulphate with barium chloride in an acidic medium and the comparison of the opalescence so obtained with standard opalescence containing a known quantity of sulphate ions

Procedure

Label two Nessler’s cylinders as Standard and Test and follow the procedure

Standard solution

  1. Pipette out 1 ml of 25% BaCl2 solutions
  2. Add 1.5 ml of ethanolic sulphate solutions
  3. Mix and allow to stand for 1 min.
  4. Add 10 ml of sulphate standard solution
  5. Add 0.15 ml of acetic acid solutions
  6. Make up the volume to 50 ml with distilled water and allow to stand for 5 min

Test solution

  1. Pipette out 1 ml of 25% BaCl2 solutions
  2. Add 1.5 ml of ethanolic sulphate solutions
  3. Mix and allow to stand for 1 min.
  4. Add 10 ml of sulphate test solution
  5. Add 0.15 ml of acetic acid solutions
  6. Make up the volume to 50 ml with distilled water and allow to stand for 5 min

Compare the opalescence produced by the test solution with a standard solution and report your result.

Reference

Indian Pharmacopoeia, ,2007, Volume 1, Pg No. 72


Limit test Chlorides, Sulphate, Iron, Heavy metals * Identification tests for Anions and Cations * Prep. & std Sodium Hydroxide, Potassium Permanganate * Assay Ferrous sulphate, Calcium gluconate, Sodium chloride, Ascorbic acid, Ibuprofen * Determination of Melting point & Boiling point * Preparation Benzoic acid from Benzamide, Picric acid from Phenol * Identification & purity test Aspirin, Caffeine


First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-IF Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I TheoryBP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I TheoryBP202T Pharmaceutical Organic Chemistry I Theory
BP103T Pharmaceutics I TheoryBP203T Biochemistry – Theory
BP104T Pharmaceutical Inorganic Chemistry TheoryBP204T Pathophysiology – Theory
BP105T Communication skills TheoryBP205T Computer Applications in Pharmacy Theory
BP106RBT Remedial BiologyBP206T Environmental sciences – Theory
BP106RMT Remedial Mathematics TheoryBP207P Human Anatomy and Physiology II Practical
BP107P Human Anatomy and Physiology PracticalBP208P Pharmaceutical Organic Chemistry I Practical
BP108P Pharmaceutical Analysis I PracticalBP209P Biochemistry Practical
BP109P Pharmaceutics I PracticalBP210P Computer Applications in Pharmacy Practical
BP110P Pharmaceutical Inorganic Chemistry Practical
BP111P Communication skills Practical
BP112RBP Remedial Biology Practical

F Y D Pharm & S Y D Pharm Notes, Books, Syllabus, PDF, Videos

First Year D PharmSecond Year D Pharm
ER20-11T Pharmaceutics TheoryER20-21T Pharmacology Theory
ER20-11P Pharmaceutics PracticalER20-21P Pharmacology Practical
ER20-12T Pharmaceutical Chemistry TheoryER20-22T Community Pharmacy & Management Theory
ER20-12P Pharmaceutical Chemistry PracticalER20-22P Community Pharmacy & Management Practical
ER20-13T Pharmacognosy TheoryER20-23T Biochemistry & Clinical Pathology Theory
ER20-13P Pharmacognosy PracticalER20-23P Biochemistry & Clinical Pathology Practical
ER20-14T Human Anatomy Physiology TheoryER20-24T Pharmacotherapeutics Theory
ER2014P Human Anatomy Physiology PracticalER20-24P Pharmacotherapeutics Practical
ER20-15T Social Pharmacy TheoryER20-25T Hospital & Clinical Pharmacy Theory
ER20-15P Social Pharmacy PracticalER20-25P Hospital & Clinical Pharmacy Practical
ER20-26T Pharmacy Law & Ethics

Suggested readings

  • Navigating the Intricacies of Subdural Space: An In-Depth Academic Exploration

  • Unraveling the Complex World of Embolization: A Comprehensive Guide

  • Unveiling Subdural Hematoma: Causes, Symptoms, and Treatment