Table of contents
BP 204T Pathophysiology Theory Syllabus
Unit I
Basic principles of Cell injury and Adaptation
Introduction, definitions, Homeostasis, Components and Types of Feedback systems,
Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage)
Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),
Cell swelling, Intracellular accumulation,
Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,
Electrolyte imbalance
Basic mechanism involved in the process of inflammation and repair
Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation, Basic principles of wound healing in the skin, Pathophysiology of Atherosclerosis
Unit II
Cardiovascular System
Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis)
Respiratory system
Asthma, Chronic obstructive airways diseases.
Renal system
Acute and chronic renal failure.
Unit III
Haematological Diseases
Iron deficiency, megaloblastic anaemia (Vit B12 and folic acid), sickle cell anaemia, thalassemia, hereditary acquired anaemia, haemophilia
Endocrine system
Diabetes, thyroid diseases, disorders of sex hormones
Nervous system
Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.
Gastrointestinal system
Peptic Ulcer
Unit IV
Hepatitis (A,B,C,D,E,F)
Alcoholic liver disease.
Diseases of bones and joints
Rheumatoid Arthritis, Osteoporosis, Gout
Principles of Cancer
Classification, etiology and pathogenesis of Cancer
Unit V
Infectious diseases
Meningitis, Typhoid, Leprosy, Tuberculosis Urinary tract infections
Sexually transmitted diseases
AIDS, Syphilis, Gonorrhea
Recommended Books (Latest Editions)
1. Vinay Kumar, Abul K. Abas, Jon C. Aster; Robbins &Cotran Pathologic Basis of Disease; South Asia edition; India; Elsevier; 2014.
2. Harsh Mohan; Textbook of Pathology; 6th edition; India; Jaypee Publications; 2010.
3. Laurence B, Bruce C, Bjorn K. ; Goodman Gilman’s The Pharmacological Basis of Therapeutics; 12 th edition; New York; McGraw-Hill; 2011.
4. Best, Charles Herbert 1899-1978; Taylor, Norman Burke 1885-1972; West, John B (John Burnard); Best and Taylor’s Physiological basis of medical practice; 12th ed; united states;
5. William and Wilkins, Baltimore;1991 [1990 printing].
6. Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston; Davidson’s Principles and Practice of Medicine; 21st edition; London; ELBS/Churchill Livingstone; 2010.
7. Guyton A, John .E Hall; Textbook of Medical Physiology; 12 th edition; WB Saunders Company; 2010.
8. Joseph DiPiro, Robert L. Talbert, Gary Yee, Barbara Wells, L. Michael Posey; Pharmacotherapy: A Pathophysiological Approach; 9 th edition; London; McGraw-Hill Medical; 2014.
9. V. Kumar, R. S. Cotran and S. L. Robbins; Basic Pathology; 6 th edition; Philadelphia; WB Saunders Company; 1997.
10. Roger Walker, Clive Edwards; Clinical Pharmacy and Therapeutics; 3rd edition; London; Churchill Livingstone publication; 2003.
Recommended Journals
1. The Journal of Pathology. ISSN: 1096-9896 (Online)
2. The American Journal of Pathology. ISSN: 0002-9440
3. Pathology. 1465-3931 (Online)
4. International Journal of Physiology, Pathophysiology and Pharmacology. ISSN: 1944-8171 (Online)
5. Indian Journal of Pathology and Microbiology. ISSN-0377-4929.
For detailed syllabus of all other subjects of Bachelor of Pharmacy (B.Pharm), 2019 regulation do visit B.Pharm 2nd Sem Subjects syllabus for 2019 regulation.
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
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