Inflammatory bowel diseases
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
Ulcerative colitis and Crohn’s disease are the main types of IBD.
Inflammation of the rectal and sigmoid colon (40-50%) is called proctitis.
40% is left sided colitis.
20% is about extensive colitis.
Inflammation of the ileum and caecum (ileo-caecal) region is about 40%.
30-40% inflammation in segments of small intestine cause skip lesions.
10% is perianal.
20% is Crohn’s colitis.
Cramps and muscle spasm
Genetics (anti microbial peptides).
Chronic diarrhoea lasts for More than 4 weeks.
Mesalazine therapy- which reduces acute inflammation.
Corticosteroids- for immune suppression
Fluids for dehydration
TNF alpha antagonists like infliximab, and adalimumab.