502T Industrial Pharmacy Theory

Industrial Pharmacy Theory syllabus

UNIT 1 Preformulation Studies

Introduction to pre-formulation, goals and objectives, the study of physicochemical characteristics of drug substances.
a. Physical properties: Physical form (crystal & amorphous), particle size, shape, flow properties, solubility profile (pKa, pH, partition coefficient), polymorphism
b. Chemical Properties: Hydrolysis, oxidation, reduction, racemization, polymerization

BCS classification of drugs & its significant

Application of pre-formulation considerations in the development of solid, liquid oral, and parenteral dosage forms and its impact on the stability of dosage forms.

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Unit 1 Preformulation Studies MCQ

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UNIT 2 Tablets

a. Introduction, ideal characteristics of tablets, classification of tablets. Excipients, Formulation of tablets, granulation methods, compression, and processing problems.
Equipment and tablet tooling.

b. Tablet coating: Types of coating, coating materials, formulation of the coating composition, methods of coating, equipment employed, and defects in the coating.

c. Quality control tests: In-process and finished product tests

Liquid orals:
Formulation and manufacturing consideration of syrups and elixirs suspensions and emulsions;
Filling and packaging;
evaluation of liquid orals

Official in Pharmacopoeia

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Unit 2 Tablets MCQ

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UNIT 3 Capsules

a. Hard gelatin capsules:
Introduction,
Production of hard gelatin capsule shells. size of capsules,
Filling, finishing, and special techniques of formulation of hard gelatin capsules,
manufacturing defects.
In-process and final product quality control tests for capsules.

b. Soft gelatin capsules:
Nature of shell and capsule content, size of capsules, the importance of base adsorption and minim/gram factors,
production,
in-process and final product quality control tests.
Packing,
storage and stability testing of soft gelatin capsules and their applications.

Pellets:
Introduction,
formulation requirements,
pelletization process,
equipment for the manufacture of pellets

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Unit 3 Capsules MCQ

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UNIT 4 Parenteral Products

a. Definition, types, advantages, and limitations. Preformulation factors and essential requirements, vehicles, additives, the importance of isotonicity

b. Production procedure, production facilities and controls, aseptic processing

c. Formulation of injections, sterile powders, large volume parenteral and lyophilized products.

d. Containers and closures selection, filling and sealing of ampoules, vials, and infusion fluids. Quality control tests of parenteral products.

Ophthalmic Preparations:

Introduction, formulation considerations;
formulation of eye drops, eye ointments, and eye lotions; methods of preparation; labelling, containers;
evaluation of ophthalmic preparations

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Unit 4 Parenteral Products MCQ

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UNIT 5 Cosmetics

Formulation and preparation of the following cosmetic preparations:
lipsticks, shampoos, cold cream and vanishing cream, toothpaste, hair dyes and
sunscreens.

Pharmaceutical Aerosols:
Definition, propellants, containers, valves, types of aerosol systems; formulation and manufacture of aerosols; Evaluation of aerosols; Quality control and stability studies.

Packaging Materials Science:
Materials used for packaging of pharmaceutical products, factors influencing the choice of containers, legal and official requirements for containers, stability aspects of packaging materials, and quality control tests.

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Unit 5 Cosmetics MCQ

Unit 5 Pharmaceutical Aerosols MCQ

Unit 5 Packaging Material MCQ

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Industrial Pharmacy Recommended Books: (Latest Editions)

1. Pharmaceutical dosage forms – Tablets, volume 1 -3 by H.A. Liberman, Leon Lachman & J.B.Schwartz
2. Pharmaceutical dosage form – Parenteral medication vol- 1&2 by Liberman & Lachman
3. Pharmaceutical dosage form disperse system VOL-1 by Liberman & Lachman
4. Modern Pharmaceutics by Gilbert S. Banker & C.T. Rhodes, 3rd Edition
5. Remington: The Science and Practice of Pharmacy, 20th edition Pharmaceutical Science (RPS)
6. Theory and Practice of Industrial Pharmacy by Liberman & Lachman
7. Pharmaceutics- The science of dosage form design by M.E.Aulton, Churchill livingstone, Latest edition
8. Introduction to Pharmaceutical Dosage Forms by H. C.Ansel, Lea &Febiger, Philadelphia, 5thedition, 2005
9. Drug stability – Principles and practice by Cartensen & C.J. Rhodes, 3rd Edition, Marcel Dekker Series, Vol 107.

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Third Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

T Y B Pharm Sem V	T Y B Pharm Sem VI
BP501T Medicinal Chemistry II Theory	BP601T Medicinal Chemistry III Theory
BP502T Industrial Pharmacy Theory	BP602T Pharmacology III Theory
BP503T Pharmacology II Theory	BP603T Herbal Drug Technology Theory
BP504T Pharmacognosy II Theory	BP604T Biopharmaceutics and Pharmacokinetics Theory
BP505T Pharmaceutical Jurisprudence Theory	BP605T Pharmaceutical Biotechnology – Theory
BP506P Industrial Pharmacy I Practical	BP606T Quality Assurance Theory
BP507P Pharmacology II Practical	BP607P Medicinal chemistry III Practical
BP508P Pharmacognosy II Practical	BP608P Pharmacology III Practical
	BP609P Herbal Drug Technology Practical

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Suggested readings:

• BP103T. Pharmaceutics I Theory syllabus
• BP606T Quality Assurance Theory
• Tocilizumab injections suspected spurious formulations: DCGI raises alarm
• Branches of Pharmacy
• BP110P Pharmaceutical Inorganic Chemistry Practical

Recommended readings:

• b pharmacy syllabus
• Pharmaceutics I practical
• Social Pharmacy Theory
• Pharmaceutical Microbiology Theory
• human anatomy and physiology
• Pathophysiology
• Pharmaceutical Analysis I Theory
• Poliomyelitis
• BIOSTATISTICS AND RESEARCH METHODOLOGY Theory
• Emulsions
• Pharmaceutical Regulatory Science

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