## Preformulation Studies MCQ with Answers

Preformulation Studies MCQ with Answers are as follows

**Crystal form shows this structure**

3D

2D

Short-range

None of the above

3D

2D

Short-range

None of the above

Answer: 3D

**Preformulation is about ensuring**

Stability

Safety

Efficacy

All of the above

Stability

Safety

Efficacy

All of the above

Answer: All of the above

**X-ray diffraction pattern indicates**

Solubility

Crystallinity

Functional groups

Permeability

Solubility

Crystallinity

Functional groups

Permeability

Answers: Crystallinity

**Monotropic polymorph can change into another form**

reversibly

irreversibly

does not change

None of the above

reversibly

irreversibly

does not change

None of the above

Answers: irreversibly

**The relationship between pH and the solubility and pKa value of an acidic drug is given by**

Henderson Hasselbalch equation

Bragg’s Equation

Noye’s Whitney Equation

All of the above

Henderson Hasselbalch equation

Bragg’s Equation

Noye’s Whitney Equation

All of the above

Answers: Henderson Hasselbalch equation

**The solubility of the pure form of API is determined by**

Partition coefficient

Phase solubility study

Permeability study

All of the above

Partition coefficient

Phase solubility study

Permeability study

All of the above

Answers: Phase solubility study

**Flow property can be improved by**

Glidant

Plasticizer

Binder

All of the above

Glidant

Plasticizer

Binder

All of the above

Answers: Glidant

**Carr’s Index is related to**

Flow property

Solubility

Partition coefficient

All of the above

Flow property

Solubility

Partition coefficient

All of the above

Answers: Flow property

**Negative Log of acid dissociation constant is**

pOH

pKa

pH

Log P

pOH

pKa

pH

Log P

Answers: pKa

**Infra-Red spectroscopy is used for determining**

Particle size

Crystallinity

Functional groups

Shape

Particle size

Crystallinity

Functional groups

Shape

Answers: Functional groups

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