May 20, 2024

Preformulation Studies MCQ with Answers

Preformulation Studies MCQ with Answers

Preformulation Studies MCQ with Answers are as follows

Crystal form shows this structure
3D
2D
Short-range
None of the above

Answer: 3D

Preformulation is about ensuring
Stability
 Safety
 Efficacy
All of the above

Answer: All of the above

X-ray diffraction pattern indicates
Solubility
Crystallinity
Functional groups
Permeability

Answers: Crystallinity

Monotropic polymorph can change into another form
reversibly
irreversibly
does not change
None of the above

Answers: irreversibly

The relationship between pH and the solubility and pKa value of an acidic drug is given by
Henderson Hasselbalch equation
Bragg’s Equation
Noye’s Whitney Equation
All of the above

Answers: Henderson Hasselbalch equation

The solubility of the pure form of API is determined by
Partition coefficient
Phase solubility study
Permeability study
All of the above

Answers: Phase solubility study

Flow property can be improved by
Glidant
Plasticizer
Binder
All of the above

Answers: Glidant

Carr’s Index is related to
Flow property
Solubility
Partition coefficient
All of the above

Answers: Flow property

Negative Log of acid dissociation constant is
pOH
pKa
pH
Log P

Answers: pKa

Infra-Red spectroscopy is used for determining
Particle size
Crystallinity
Functional groups
Shape

Answers: Functional groups


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