BP503T PHARMACOLOGY II Theory

Pharmacology II Theory syllabus

UNIT I

Pharmacology of drugs acting on the cardiovascular system
a. Introduction to hemodynamic and electrophysiology of the heart.
b. Drugs used in congestive heart failure
c. Anti-hypertensive drugs.
d. Anti-anginal drugs.
e. Anti-arrhythmic drugs.
f. Anti-hyperlipidemic drugs.

UNIT II

Pharmacology of drugs acting on the cardiovascular system
a. A drug used in the therapy of shock.
b. Hematinics, coagulants, and anticoagulants.
c. Fibrinolytics and anti-platelet drugs
d. Plasma volume expanders

Pharmacology of drugs acting on the urinary system
a. Diuretics
b. Anti-diuretics

UNIT III

Autocoids and related drugs
a. Introduction to autacoids and classification
b. Histamine, 5-HT, and their antagonists.
c. Prostaglandins, Thromboxanes, and Leukotrienes.
d. Angiotensin, Bradykinin, and Substance P.
e. Non-steroidal anti-inflammatory agents
f. Anti-gout drugs
g. Antirheumatic drugs

UNIT IV

Pharmacology of drugs acting on an endocrine system
a. Basic concepts in endocrine pharmacology.
b. Anterior Pituitary hormones- analogs and their inhibitors.
c. Thyroid hormones- analogs and their inhibitors.
d. Hormones regulating plasma calcium level- Parathormone, Calcitonin and
Vitamin-D.
d. Insulin, Oral Hypoglycemic Agents, and glucagon.
e. ACTH and corticosteroids.

UNIT V

Pharmacology of drugs acting on an endocrine system
a. Androgens and Anabolic steroids.
b. Estrogens, progesterone, and oral contraceptives.
c. Drugs acting on the uterus.

Bioassay
a. Principles and applications of bioassay.
b.Types of bioassay
c. Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis, histamine
and 5-HT

Recommended Books (Latest Editions)

  1. Rang H. P., Dale M. M., Ritter J. M., Flower R. J., Rang and Dale’s Pharmacology,
    Churchil Livingstone Elsevier
  2. Katzung B. G., Masters S. B., Trevor A. J., Basic and clinical pharmacology, Tata Mc
    Graw-Hill.
  3. Goodman and Gilman’s, The Pharmacological Basis of Therapeutics
  4. Marry Anne K. K., Lloyd Yee Y., Brian K. A., Robbin L.C., Joseph G. B., Wayne A.
    K., Bradley R.W., Applied Therapeutics, The Clinical use of Drugs, The Point
    Lippincott Williams & Wilkins.
  5. Mycek M.J, Gelnet S.B and Perper M.M. Lippincott’s Illustrated Reviews-
    Pharmacology.
  6. K.D.Tripathi. Essentials of Medical Pharmacology, , JAYPEE Brothers Medical
    Publishers (P) Ltd, New Delhi.
  7. Sharma H. L., Sharma K. K., Principles of Pharmacology, Paras medical publisher
  8. Modern Pharmacology with clinical Applications, by Charles R.Craig& Robert.
  9. Ghosh MN. Fundamentals of Experimental Pharmacology. Hilton & Company,
    Kolkata.
  10. Kulkarni SK. Handbook of experimental pharmacology. Vallabh Prakashan.

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