Pharmacology Practical D Pharm
Introduction to the following topics pertaining to experimental pharmacology has to be discussed and documented in the practical manuals.
- Introduction to experimental pharmacology
- Study of laboratory animals (a) Mice; (b) Rats; (c) Guinea pigs; (d) Rabbits
- Commonly used instruments in experimental pharmacology
- Different routes of administration of drugs in animals
- Types of pre-clinical experiments: In-Vivo, In-Vitro, Ex-Vivo, etc.
- Techniques of blood collection from animals
Experiments
Note: Animals shall not be used for doing/demonstrating any of the experiments given. The given experiments shall be carried- out / demonstrated as the case may be, ONLY with the use of software program(s) such as ‘Ex Pharm’ or any other suitable software
- Study of local anaesthetics on rabbit eye
- Study of Mydriatic effect on rabbit eye
- Study of Miotic effect on rabbit eye
- Effect of analgesics using Analgesiometer
- Study of analgesic activity by writhing test
- Screening of anti-convulsant using Electro Convulsiometer
- Screening of Muscle relaxants using Rota-Rod apparatus
- Screening of CNS stimulants and depressants using Actophotometer
- Study of anxiolytic activity using elevated plus maze method
- Study of effect of drugs (any 2) on isolated heart
- Effect of drugs on ciliary motility on frog’s buccal cavity
- Pyrogen testing by rabbit method
Assignments
The students shall be asked to submit written assignments on the following topics (One assignment per student per sessional period. i.e., a minimum of THREE assignments per student)
- Introduction to Allergy Testing
- Introduction to Toxicity Studies
- Drug Facts Labels of US FDA
- Pre-clinical studies in new drug development
- Medicines and meals: Before or After food
- Pre-clinical studies in new drug development
- Drugs available as paediatric formulations
- Drug information apps
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