Pharmacology Practical D Pharm

Introduction to the following topics pertaining to experimental pharmacology has to be discussed and documented in the practical manuals.

1. Introduction to experimental pharmacology
2. Study of laboratory animals (a) Mice; (b) Rats; (c) Guinea pigs; (d) Rabbits
3. Commonly used instruments in experimental pharmacology
4. Different routes of administration of drugs in animals
5. Types of pre-clinical experiments: In-Vivo, In-Vitro, Ex-Vivo, etc.
6. Techniques of blood collection from animals

Experiments

Note: Animals shall not be used for doing/demonstrating any of the experiments given. The given experiments shall be carried- out / demonstrated as the case may be, ONLY with the use of software program(s) such as ‘Ex Pharm’ or any other suitable software

1. Study of local anaesthetics on rabbit eye
2. Study of Mydriatic effect on rabbit eye
3. Study of Miotic effect on rabbit eye
4. Effect of analgesics using Analgesiometer
5. Study of analgesic activity by writhing test
6. Screening of anti-convulsant using Electro Convulsiometer
7. Screening of Muscle relaxants using Rota-Rod apparatus
8. Screening of CNS stimulants and depressants using Actophotometer
9. Study of anxiolytic activity using elevated plus maze method
10. Study of effect of drugs (any 2) on isolated heart
11. Effect of drugs on ciliary motility on frog’s buccal cavity
12. Pyrogen testing by rabbit method

Assignments

The students shall be asked to submit written assignments on the following topics (One assignment per student per sessional period. i.e., a minimum of THREE assignments per student)

1. Introduction to Allergy Testing
2. Introduction to Toxicity Studies
3. Drug Facts Labels of US FDA
4. Pre-clinical studies in new drug development
5. Medicines and meals: Before or After food
6. Pre-clinical studies in new drug development
7. Drugs available as paediatric formulations
8. Drug information apps

D Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

Suggested readings:

• BP801T Biostatistics and Research Methodology Theory, Notes, PDF, Books
• BP408P Pharmacology I Practical
• ER20-15P Social Pharmacy Practical D Pharm
• ER20-25P Hospital & Clinical Pharmacy Practical D Pharm
• ER20-11P Pharmaceutics Practical D Pharm
• b pharmacy syllabus
• History of microbiology