Test for pyrogens rabbit method: Pharmacology Practical Lab Manual PDF

Aim

To prepare and submitted preliminary test (sham test) and rabbit pyroxene test.

Methodology

Groups of three healthy nature rabbits are chosen. Accurate thermometers are inserted into the rectum of the rabbits to record their body temperature. Test solutions are warmed to 370C prior to injection. Rabbit temperatures are recorded at 30min intervals between 1 and 3hr.

Procedure

Inject the solution (38.5⁰C) under examination slowly into the marina (vein of the ear of each rabbit) over a period of exceeding 4 minutes unless otherwise prescribed in the monograph. Record the temperature of each animal at half-hourly intervals for 3 hours after the injection.

Observation

The difference between the initial temp and the maximum temperature which is the highest temp recorded for rabbits taken to be its response.

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Third Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

T Y B Pharm Sem V	T Y B Pharm Sem VI
BP501T Medicinal Chemistry II Theory	BP601T Medicinal Chemistry III Theory
BP502T Industrial Pharmacy Theory	BP602T Pharmacology III Theory
BP503T Pharmacology II Theory	BP603T Herbal Drug Technology Theory
BP504T Pharmacognosy II Theory	BP604T Biopharmaceutics and Pharmacokinetics Theory
BP505T Pharmaceutical Jurisprudence Theory	BP605T Pharmaceutical Biotechnology – Theory
BP506P Industrial Pharmacy I Practical	BP606T Quality Assurance Theory
BP507P Pharmacology II Practical	BP607P Medicinal chemistry III Practical
BP508P Pharmacognosy II Practical	BP608P Pharmacology III Practical
	BP609P Herbal Drug Technology Practical

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Suggested readings:

• Effect of drugs on rabbit eye: Pharmacology Lab Manual
• Insulin hypoglycemic effect in the rabbit: Pharmacology III Practical
• ER20-21P Pharmacology Practical D Pharm
• Study of common laboratory animals: Pharmacology Lab
• ER20-14P Human Anatomy & Physiology Practical D Pharm

Recommended readings:

• b pharmacy syllabus

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