Solvation & association

Solvation and association are two related concepts in chemistry that describe how molecules interact with each other in a solvent.

Solvation is the process by which a solute molecule is surrounded by solvent molecules. When a solute molecule is introduced into a solvent, it can interact with the solvent molecules through various intermolecular forces, such as hydrogen bonding, dipole-dipole interactions, and van der Waals forces. These interactions can lead to the formation of a solvation shell around the solute molecule, which can help stabilize it in the solvent.

Association, on the other hand, is the process by which two or more molecules come together to form a larger molecule or complex. This can occur when the molecules have complementary structures or when they are attracted to each other through intermolecular forces. For example, association can occur between a solute and a solvent molecule if they have similar structures or if they can form hydrogen bonds with each other.

The relationship between solvation and association is complex and can depend on various factors, such as the nature of the solute and solvent, the temperature, and the concentration of the solute. In some cases, solvation can promote association, while in other cases, it can inhibit it.

For example, in the case of protein folding, the solvation of the amino acid residues is critical for stabilizing the folded structure. However, solvation can also hinder protein-protein association by creating a barrier between the molecules.

In summary, solvation and association are two related concepts that describe how molecules interact with each other in a solvent. Solvation refers to the process by which a solute molecule is surrounded by solvent molecules, while association refers to the process by which two or more molecules come together to form a larger molecule or complex. The relationship between solvation and association can be complex and depend on various factors, and understanding these processes is important in fields such as biochemistry, pharmaceuticals, and materials science.

Second Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

S Y B Pharm Sem III	S Y B Pharm Sem IV
BP301T Pharmaceutical Organic Chemistry II Theory	BP401T Pharmaceutical Organic Chemistry III Theory
BP302T Physical Pharmaceutics I Theory	BP402T Medicinal Chemistry I Theory
BP303T Pharmaceutical Microbiology Theo	BP403T Physical Pharmaceutics II Theory
BP304T Pharmaceutical Engineering Theory	BP404T Pharmacology I Theory
BP305P Pharmaceutical Organic Chemistry II Practical	BP405T Pharmacognosy I Theory
BP306P Physical Pharmaceutics I Practical	BP406P Medicinal Chemistry I Practical
BP307P Pharmaceutical Microbiology Practical	BP407P Physical Pharmaceutics II Practical
BP308P Pharmaceutical Engineering Practical	BP408P Pharmacology I Practical
	BP409P Pharmacognosy I Practical