4.4 Biostatistics & Research Methodology Syllabus, Notes, PDF, Books, MCQ, Downloads

Biostatistics and Research Methodology MCQ

1 Research Methodology

a) Types of clinical study designs:
Case studies, observational studies, interventional studies,
b) Designing the methodology
c) Sample size determination and power of a study
Determination of sample size for simple comparative experiments, determination of sample size to obtain a confidence interval of specified width, power of a study
d) Report writing and presentation of data

2 Biostatistics

2.1 a) Introduction
b) Types of data distribution
c) Measures describing the central tendency distributions- average, median, mode
d) Measurement of the spread of data range, variation of mean, standard deviation, variance, coefficient of variation, and standard error of the mean.

2.2 Data graphics
Construction and labeling of graphs, histograms, pie charts, scatter plots, semilogarithmic plots

2.3 Basics of testing hypothesis
a) Null hypothesis, level of significance, power of a test, P value, statistical estimation of confidence intervals.
b) Level of significance (Parametric data)- students t-test (paired and unpaired), chi-square test, Analysis of Variance (one-way and two-way)
c) Level of significance (Non-parametric data)- Sign test, Wilcoxon’s signed rank test, Wilcoxon rank sum test, Mann Whitney U test, Kruskal-Wall test (one way ANOVA)
d) Linear regression and correlation- Introduction, Pearson’s and Spearman’s correlation and correlation co-efficient.
e) Introduction to statistical software: SPSS, Epi Info, SAS.

2.4 Statistical methods in epidemiology
Incidence and prevalence, relative risk, attributable risk

3. Computer applications in pharmacy

Computer System in Hospital Pharmacy: Patterns of Computer use in Hospital Pharmacy – Patient record database management, Medication order entry – Drug labels and list – Intravenous solution and admixture, patient medication profiles, Inventory control, Management report & Statistics.
Computer In Community Pharmacy Computerizing the Prescription Dispensing process
Use of Computers for Pharmaceutical Care in community pharmacy Accounting and General ledger system
Drug Information Retrieval & Storage :
Introduction – Advantages of Computerized Literature Retrieval Use of Computerized Retrieval

Fourth Year Pharm D Subjects

4.1	Pharmacotherapeutics-III
4.2	Hospital Pharmacy
4.3	Clinical Pharmacy
4.4	Biostatistics & Research Methodology
4.5	Biopharmaceutics & Pharmacokinetics
4.6	Clinical Toxicology