February 18, 2025

Test for pyrogens rabbit method: Pharmacology Practical Lab Manual PDF

Test for pyrogens rabbit method: Pharmacology Practical Lab Manual PDF

Aim

To prepare and submitted preliminary test (sham test) and rabbit pyroxene test.

Methodology

Groups of three healthy nature rabbits are chosen. Accurate thermometers are inserted into the rectum of the rabbits to record their body temperature. Test solutions are warmed to 370C prior to injection. Rabbit temperatures are recorded at 30min intervals between 1 and 3hr.

Procedure

Inject the solution (38.50C) under examination slowly into the marina (vein of the ear of each rabbit) over a period of exceeding 4 minutes unless otherwise prescribed in the monograph. Record the temperature of each animal at half-hourly intervals for 3 hours after the injection.

Observation

The difference between the initial temp and the maximum temperature which is the highest temp recorded for rabbits taken to be its response.


Third Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

T Y B Pharm Sem VT Y B Pharm Sem VI
BP501T Medicinal Chemistry II TheoryBP601T Medicinal Chemistry III Theory
BP502T Industrial Pharmacy TheoryBP602T Pharmacology III Theory
BP503T Pharmacology II TheoryBP603T Herbal Drug Technology Theory
BP504T Pharmacognosy II TheoryBP604T Biopharmaceutics and Pharmacokinetics Theory
BP505T Pharmaceutical Jurisprudence TheoryBP605T Pharmaceutical Biotechnology – Theory
BP506P Industrial Pharmacy I PracticalBP606T Quality Assurance Theory
BP507P Pharmacology II PracticalBP607P Medicinal chemistry III Practical
BP508P Pharmacognosy II PracticalBP608P Pharmacology III Practical
BP609P Herbal Drug Technology Practical

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