Preparation and standardization of Sodium thiosulfate standard solution
Pharmaceutical Analysis I Practical: Limit test for (1) Chloride (2) Sulphate (3) Iron (4) Arsenic Preparation and standardisation of (1) Sodium hydroxide (2) Sulphuric acid (3) Sodium thiosulfate (4) Potassium permanganate (5) Ceric ammonium sulphate Assay (1) Ammonium chloride (2) Ferrous sulphate(3) Copper sulphate (4) Calcium gluconate (5) Hydrogen peroxide (6) Sodium benzoate (7) Sodium Chloride Determination of Normality (1) Conductometric titration of strong acid against a strong base (2) Conductometric titration of strong acid and weak acid against a strong base (3) Potentiometric titration
To Prepare and standardize 0.01 M sodium thiosulphate standard solution
The principle of standardization of sodium thiosulphate is based on redox iodometric titration with potassium iodate (or potassium bromate) as a primary standard. Potassium iodate a strong oxidizing agent is treated with excess potassium iodide in acidic media which liberates iodine which is back titrated with sodium thiosulphate
Preparation of 0.1 M Sodium thiosulfate standard solution
Dissolve____ g of sodium thiosulphate and 0.2 g of sodium carbonate in carbon dioxide-free water and dilute to 1000 ml with the same solvent.
Standardization of 0.1 M Sodium thiosulfate solution Dissolve 0.200 g of potassium bromate, weighed accurately, in sufficient water to produce 250.0 ml. To 50.0 ml of this solution add 2 g of potassium iodide and 3 ml of 2 M hydrochloric acid and titrate with the sodium thiosulphate solution using the starch solution, added towards the end of the titration, as an indicator until the blue colour is discharged.
Indian Pharmacopoeia 2014; Vol. 1; Pg. No. 316
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