
Transmissible spongiform encephalopathies
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is a virus belonging to the herpesvirus family. It’s one of the eight known human herpesviruses and is associated with several health conditions. Here’s a breakdown of what you should know about KSHV:
What does KSHV cause?
KSHV is the primary cause of Kaposi’s sarcoma (KS), a type of cancer that can develop in the skin, lymph nodes, and internal organs. KS typically presents as reddish-purple lesions and can be associated with a weakened immune system.
Other KSHV-associated conditions:
While KS is the most common condition caused by KSHV, the virus can also contribute to:
- Primary effusion lymphoma (PEL): A rare cancer of the body cavities.
- Multicentric Castleman disease (MCD): A non-cancerous disorder affecting the lymph nodes.
- KSHV inflammatory cytokine syndrome (KICS): A condition causing fever, fatigue, and muscle pain.
How is KSHV transmitted?
KSHV is primarily transmitted through saliva, although other bodily fluids might play a role in transmission. Sharing utensils, close contact with unhealed sores, and possibly sexual contact can all be potential transmission routes.
KSHV infection and symptoms:
KSHV infection is very common, and many people who are infected never develop any symptoms or health problems. In fact, most people contract KSHV during childhood without even realizing it.
Risk factors for KSHV complications:
A weakened immune system due to HIV/AIDS, organ transplantation medications, or certain medical conditions can increase the risk of developing health problems after KSHV infection.
Diagnosis of KSHV infection:
A blood test can detect the presence of KSHV antibodies, indicating past or current infection. However, a positive antibody test doesn’t necessarily mean you have an active KSHV-related illness.
Treatment for KSHV infection:
There’s no specific treatment for KSHV infection itself. However, if you have a weakened immune system and develop KS or other KSHV-related conditions, treatment will focus on managing those specific conditions.
Prevention of KSHV infection:
There’s no vaccine available to prevent KSHV infection. Practicing good hygiene habits like frequent handwashing and avoiding close contact with people who have open sores can help reduce the risk of transmission.
Here are some key takeaways:
- KSHV is a common virus that can cause Kaposi’s sarcoma and some other conditions, but most people with KSHV infection never experience any health problems.
- A weakened immune system increases the risk of KSHV-related complications.
- There’s no specific treatment for KSHV infection, but treatments exist for KSHV-associated conditions.
If you have concerns about KSHV infection or symptoms like those of Kaposi’s sarcoma, consult a healthcare professional for proper diagnosis and guidance.