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2.1 Pathophysiology Pharm D Syllabus, Notes, PDF, Books, Downloads, MCQ

1 Basic principle of cell injury and Adaptation

a) Causes, Pathogenesis and morphology of cell injury
b) Abnormalities in lipoproteinaemia, glycogen infiltration and glycogen infiltration and glycogen infiltration and glycogen storage diseases

2 Inflammation

a) Pathogenesis of acute inflammation, Chemical mediators in inflammation, Types of chronic inflammation
b) Repairs of wounds in the skin, factors influencing healing of wounds

3 Diseases of Immunity

a) Introduction to Tand B cells
b) MHC proteins or transplantation antigens
c) Immune tolerance
– Hypersensitivity
Hypersensitivity type I, II, III, IV, Biological significance, Allergy due to food, chemicals and drugs
– Autoimmunity
Criteria for autoimmunity, Classifications of autoimmune diseases in man, mechanism of autoimmunity, Transplantation and immunologic tolerance, allograft rejections, transplantation antigens, mechanism of rejection of the allograft.
– Acquired immune deficiency syndrome (AIDS)
– Amyloidosis

4 Cancer

Differences between benign and malignant tumours, Histological diagnosis of malignancy, invasions and metastasis, patterns of spread, disturbances of growth of cells, classification of tumours, general biology of tumours, the spread of malignant tumours, etiology and pathogenesis of cancer.

5 Types of shock, mechanisms, stages and management

6 Biological effects of radiation

7 Environmental and nutritional diseases

i) Air pollution and smoking- SO2, NO, NO2, and CO
ii) Protein calorie malnutrition, vitamins, obesity, and the pathogenesis of starvation.

8 Pathophysiology of common diseases

a. Parkinsonism
b. Schizophrenia
c. Depression and mania
d. Hypertension,
e. Stroke (ischaemic and haemorrhage)
f. Angina, CCF, Atherosclerosis, Myocardial infarction
g. Diabetes Mellitus
h. Peptic ulcer and inflammatory bowel diseases
i. Cirrhosis and Alcoholic liver diseases
j. Acute and chronic renal failure
k. Asthma and chronic obstructive airway diseases

9 Infectious diseases :

Sexually transmitted diseases (HIV, Syphilis, Gonorrhea), Urinary tract infections, Pneumonia, Typhoid, Tuberculosis, Leprosy, Malaria Dysentery (bacterial and amoebic ), Hepatitis- infective hepatitis.

Assignment

1 Chemical Mediators of inflammation
2 Drug Hypersensitivity
3 Cigarette smoking & its ill effects
4 Biological Effects of Radiation
5 Etiology and hazards of obesity
6 Complications of diabetes
7 Diagnosis of cancer
8 Disorders of vitamins
9 Methods in Pathology-Laboratory values of clinical significance

10 Pathophysiology of Dengue Hemorrhagic Fever (DHF)

Second Year Pharm D Subjects

2.1Pathophysiology
2.2Pharmaceutical  Microbiology
2.3Pharmacognosy & Phytopharmaceuticals
2.4Pharmacology-I
2.5Community Pharmacy
2.6Pharmacotherapeutics-I

Suggested Readings

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