February 23, 2024

Lycopene: Occurrence, chemical nature and medicinal benefits

Lycopene: Occurrence, chemical nature and medicinal benefits


Lycopene is a bright red carotenoid pigment that is found in high concentrations in certain fruits and vegetables, especially in tomatoes. It is a member of the carotenoid family, which includes other pigments like beta-carotene and alpha-carotene.

In addition to tomatoes, lycopene is also found in watermelon, papaya, grapefruit, guava, and rosehips. In fact, the redder the fruit or vegetable, the higher the concentration of lycopene it is likely to contain.

Tomatoes and tomato-based products are the richest dietary sources of lycopene. However, it’s important to note that lycopene is more easily absorbed by the body when it is consumed with fat, so cooking tomatoes in olive oil, for example, can help to increase the bioavailability of lycopene.

Lycopene is not produced by the human body, so it must be obtained through diet or supplementation. Studies have suggested that a diet high in lycopene may be associated with several potential health benefits, including a reduced risk of certain types of cancer, cardiovascular disease, and age-related macular degeneration.

Chemical Nature

Lycopene is a bright red carotenoid pigment found in many fruits and vegetables, particularly in tomatoes, watermelon, pink grapefruit, and papaya. It is a type of acyclic carotenoid, which means that it has a linear molecular structure rather than a cyclic structure like other carotenoids such as beta-carotene.

Chemically, lycopene is a tetraterpenoid, which means that it is composed of eight isoprene units. Its molecular formula is C40H56, and it has a molecular weight of 536.88 g/mol. Lycopene has a long, rigid, and linear molecule with 13 conjugated double bonds, which gives it its deep red color and strong antioxidant properties.

Lycopene is not converted into vitamin A in the body like beta-carotene, but it still has several potential health benefits. It is a potent antioxidant that may help to protect against oxidative damage and inflammation, which are involved in the development of many chronic diseases such as cancer, heart disease, and Alzheimer’s disease. Some studies have also suggested that lycopene may have a protective effect against prostate cancer and may help to improve skin health by reducing sun damage and premature aging

Medicinal benefits

Lycopene is a naturally occurring pigment that belongs to the carotenoid family. It is found in high concentrations in tomatoes, watermelon, pink grapefruit, and other red or pink fruits and vegetables.

Lycopene is a powerful antioxidant and has several potential medicinal benefits:

  1. May reduce the risk of cancer: Some studies have suggested that lycopene may help to reduce the risk of certain types of cancer, such as prostate cancer, breast cancer, and lung cancer.
  2. May improve heart health: Lycopene may help to improve heart health by reducing inflammation and oxidative stress in the body, lowering blood pressure, and improving cholesterol levels.
  3. May protect against sun damage: Lycopene may help to protect the skin from sun damage and reduce the risk of skin cancer.
  4. May improve vision: Lycopene may help to improve vision and protect against age-related macular degeneration.
  5. May improve male fertility: Some studies have suggested that lycopene may help to improve sperm quality and reduce the risk of infertility in men.

Overall, lycopene is an important nutrient with potential medicinal benefits. However, it’s important to obtain lycopene from whole foods rather than supplements, as high-dose supplements may be harmful in some cases.

Final Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

Final Year B Pharm Sem VIIBP701T Instrumental Methods of Analysis Theory
BP702T Industrial Pharmacy TheoryBP703T Pharmacy Practice Theory
BP704T Novel Drug Delivery System TheoryBP705 P Instrumental Methods of Analysis Practical
Final Year B Pharm Sem VIIBP801T Biostatistics and Research Methodology Theory
BP802T Social and Preventive Pharmacy TheoryBP803ET Pharmaceutical Marketing Theory
BP804ET Pharmaceutical Regulatory Science TheoryBP805ET Pharmacovigilance Theory
BP806ET Quality Control and Standardization of Herbals TheoryBP807ET Computer-Aided Drug Design Theory
BP808ET Cell and Molecular Biology TheoryBP809ET Cosmetic Science Theory
BP810ET Experimental Pharmacology TheoryBP811ET Advanced Instrumentation Techniques Theory
BP812ET Dietary supplements and NutraceuticalsPharmaceutical Product Development

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