Principles and applications of Iodimetry

Principles and applications of Iodimetry

Iodimetry is a quantitative analytical method used to determine the concentration of reducing agents, such as thiosulfate, sulfite, and ascorbic acid. The method is based on the reduction of iodine (I2) to iodide (I-) by a reducing agent, which can be quantitatively measured by titrating the iodine with a standard solution of a thiosulfate or other reducing agent.

The principle of iodimetry involves the oxidation of the reducing agent by iodine under acidic conditions to produce iodide ions. The iodine is added to the sample containing the reducing agent, and the excess iodine is then titrated with a standard solution of a reducing agent, such as sodium thiosulfate, until the iodine is completely consumed. The endpoint of the titration is indicated by a color change, typically from brown to colorless, or by the use of a starch indicator, which forms a blue-black complex with excess iodine.

Iodimetry has a wide range of applications in various fields, including:

1. Analytical chemistry: Iodimetry is used for the quantitative determination of various reducing agents in analytical chemistry, including sulfite, thiosulfate, and ascorbic acid. The method is widely used in the food and beverage industry for the determination of sulfite in wine, beer, and other beverages.
2. Pharmaceutical industry: Iodimetry is used for the determination of the concentration of reducing agents, such as ascorbic acid, in pharmaceuticals. It is also used for the determination of the purity of certain drugs, such as vitamin C.
3. Water and wastewater treatment: Iodimetry is used for the determination of the concentration of thiosulfate and other reducing agents in water and wastewater treatment processes.
4. Industrial processes: Iodimetry is used for the determination of the concentration of reducing agents in various industrial processes, including the pulp and paper industry and the textile industry.

Overall, iodimetry is a useful analytical method for the determination of the concentration of reducing agents, and its applications span various industries and fields.

First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-I	F Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I Theory	BP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I Theory	BP202T Pharmaceutical Organic Chemistry I Theory
BP103T Pharmaceutics I Theory	BP203T Biochemistry – Theory
BP104T Pharmaceutical Inorganic Chemistry Theory	BP204T Pathophysiology – Theory
BP105T Communication skills Theory	BP205T Computer Applications in Pharmacy Theory
BP106RBT Remedial Biology	BP206T Environmental sciences – Theory
BP106RMT Remedial Mathematics Theory	BP207P Human Anatomy and Physiology II Practical
BP107P Human Anatomy and Physiology Practical	BP208P Pharmaceutical Organic Chemistry I Practical
BP108P Pharmaceutical Analysis I Practical	BP209P Biochemistry Practical
BP109P Pharmaceutics I Practical	BP210P Computer Applications in Pharmacy Practical
BP110P Pharmaceutical Inorganic Chemistry Practical
BP111P Communication skills Practical
BP112RBP Remedial Biology Practical

Suggested readings:

• Sodium thiosulphate: Preparation and standardization of molar and normal solutions
• Iodine Gargle Pharmaceutics I Practical
• Aqueous Iodine solution / Lugol’s solution
• Use of microorganism in industry
• 3.5 Medicinal Chemistry Pharm D Notes, PDF, Books, MCQ, Downloads