February 23, 2024

810ET Experimental Pharmacology Theory

Experimental Pharmacology Theory, Notes, PDF Books, MCQ

Unit I

Laboratory Animals:
Study of CPCSEA and OECD guidelines for maintenance, breeding
and conduct of experiments on laboratory animals, Common lab
animals: Description and applications of different species and strains
of animals. Popular transgenic and mutant animals.
Techniques for collection of blood and common routes of drug
administration in laboratory animals, Techniques of blood collection
and euthanasia.

Unit II

Preclinical screening models
a. Introduction: Dose selection, calculation and conversions,
preparation of drug solution/suspensions, a grouping of animals and
importance of sham negative and positive control groups.
The rationale for the selection of animal species and sex for the study.
b. Study of screening animal models for
Diuretics, nootropics, anti-Parkinson’s, antiasthmatics,
Preclinical screening models: for CNS activity- analgesic,
antipyretic, anti-inflammatory, general anaesthetics, sedative and
hypnotics, antipsychotic, antidepressant, antiepileptic, anti parkinsonism, Alzheimer’s disease

Unit III

Preclinical screening models: for ANS activity, sympathomimetics,
sympatholytics, parasympathomimetics, parasympatholytics, skeletal
muscle relaxants, drugs acting on the eye, local anaesthetics

Unit IV

Preclinical screening models: for CVS activity- antihypertensives,
diuretics, antiarrhythmic, antidyslepidemic, anti aggregatory,
coagulants, and anticoagulants
Preclinical screening models for other important drugs like antiulcer, antidiabetic, anticancer and antiasthmatics.
Research methodology and Bio-statistics
Selection of research topic, review of literature, research hypothesis and study design
Pre-clinical data analysis and interpretation using Students ‘t’ test
and one-way ANOVA. Graphical representation of data

  1. Fundamentals of experimental Pharmacology-byM.N.Ghosh
  2. Hand book of Experimental Pharmacology-S.K.Kulakarni
  3. CPCSEA guidelines for laboratory animal facility.
  4. Drug discovery and Evaluation by Vogel H.G.
  5. Drug Screening Methods by Suresh Kumar Gupta and S. K. Gupta
  6. Introduction to biostatistics and research methods by PSS Sundar Rao and J Richard

Final Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

Final Year B Pharm Sem VIIBP701T Instrumental Methods of Analysis Theory
BP702T Industrial Pharmacy TheoryBP703T Pharmacy Practice Theory
BP704T Novel Drug Delivery System TheoryBP705 P Instrumental Methods of Analysis Practical
Final Year B Pharm Sem VIIBP801T Biostatistics and Research Methodology Theory
BP802T Social and Preventive Pharmacy TheoryBP803ET Pharmaceutical Marketing Theory
BP804ET Pharmaceutical Regulatory Science TheoryBP805ET Pharmacovigilance Theory
BP806ET Quality Control and Standardization of Herbals TheoryBP807ET Computer-Aided Drug Design Theory
BP808ET Cell and Molecular Biology TheoryBP809ET Cosmetic Science Theory
BP810ET Experimental Pharmacology TheoryBP811ET Advanced Instrumentation Techniques Theory
BP812ET Dietary supplements and NutraceuticalsPharmaceutical Product Development

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