2,3-diphenyl quinoxaline synthesis from o-phenylenediamine

2,3-diphenyl quinoxaline synthesis from o-phenylenediamine

AIM:

To synthesize and submit 2,3-diphenyl quinoxaline from o-phenylenediamine and report its percentage yield.

REFERENCE:

1. Vogels textbook of practical organic chemistry,5th edition, page no:90.
2. Comprehensive practical organic chemistry by V.K.Ahluwalia and Renu Aggarwal, page no:123.

CHEMICAL REQUIREMENTS:

o-phenylenediamine, benzil, rectified spirit.

PRINCIPLE:

Quinoxalines are a type of heterocyclic compounds. They are also known as benzopyrazines.

Generally quinoxaline is formed by the condensation of o-phenylenediamine with diketones. Here 2,3-diphenyl quinoxaline is prepared by treating o-phenylenediamine with benzil

PROCEDURE:

Add a solution of 1.1g of o-phenylenediamine in 8ml rectified spirit to a warm solution of 2.1g of benzil in 8ml rectified spirit. Warm the mixture for 30 minutes in a water bath. Add water dropwise until slight cloudiness persists. Cool the solution and filter the product.

USE:

Quinoxaline derivatives are used as antimicrobial agents like levomycin. They are also used in dyes.

REPORT:

2,3-diphenyl quinoxaline was prepared and submitted. The percentage yield was found to be ———

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