2,3-diphenyl quinoxaline synthesis from o-phenylenediamine
To synthesize and submit 2,3-diphenyl quinoxaline from o-phenylenediamine and report its percentage yield.
- Vogels textbook of practical organic chemistry,5th edition, page no:90.
- Comprehensive practical organic chemistry by V.K.Ahluwalia and Renu Aggarwal, page no:123.
o-phenylenediamine, benzil, rectified spirit.
Quinoxalines are a type of heterocyclic compounds. They are also known as benzopyrazines.
Generally quinoxaline is formed by the condensation of o-phenylenediamine with diketones. Here 2,3-diphenyl quinoxaline is prepared by treating o-phenylenediamine with benzil
Add a solution of 1.1g of o-phenylenediamine in 8ml rectified spirit to a warm solution of 2.1g of benzil in 8ml rectified spirit. Warm the mixture for 30 minutes in a water bath. Add water dropwise until slight cloudiness persists. Cool the solution and filter the product.
Quinoxaline derivatives are used as antimicrobial agents like levomycin. They are also used in dyes.
2,3-diphenyl quinoxaline was prepared and submitted. The percentage yield was found to be ———