February 18, 2025

704T Novel Drug Delivery Systems NDDS Theory, Notes, PDF

Novel Drug Delivery Systems NDDS Theory, Notes, PDF

Unit-I

Controlled drug delivery systems

Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates.

Approaches to design controlled release formulations based on diffusion, dissolution and ion exchange principles.

Physicochemical and biological properties of drugs relevant to controlled release formulations

Polymers

Introduction, classification, properties, advantages and application of polymers in the formulation of controlled release drug delivery systems.


Unit-II

Microencapsulation

Definition, advantages and disadvantages, microspheres /microcapsules, microparticles, methods of microencapsulation, applications

Mucosal Drug Delivery system

Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems

Implantable Drug Delivery Systems

Introduction, advantages and disadvantages, the concept of implants and osmotic pump


Unit-III

Transdermal Drug Delivery Systems

Introduction, Permeation through the skin, factors affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches

Gastroretentive drug delivery systems

Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high-density systems, inflatable and gastroadhesive systems and their applications

Nasopulmonary drug delivery system

Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers


Unit-IV

Targeted drug Delivery

Concepts and approaches advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications


Unit-V

Ocular Drug Delivery Systems

Introduction, intraocular barriers and methods to overcome Preliminary study, ocular formulations and ocuserts

Intrauterine Drug Delivery Systems

Introduction, advantages and disadvantages, development of intrauterine devices (IUDs) and applications


  1. Y W. Chien, Novel Drug Delivery Systems, 2nd edition, revised and expanded, Marcel Dekker, Inc., New York, 1992.
  2. Robinson, J. R., Lee V. H. L, Controlled Drug Delivery Systems, Marcel Dekker, Inc., New York, 1992.
  3. Encyclopedia of Controlled Delivery. Edith Mathiowitz, Published by Wiley Interscience Publication, John Wiley and Sons, Inc, New York. Chichester/Weinheim
  4. N.K. Jain, Controlled and Novel Drug Delivery, CBS Publishers & Distributors, New Delhi, First edition 1997 (reprint in 2001).
  5. S.P. Vyas and R.K. Khar, Controlled Drug Delivery -concepts and advances, Vallabh Prakashan, New Delhi, First edition 2002.

Journals

  1. Indian Journal of Pharmaceutical Sciences (IPA)
  2. Indian Drugs (IDMA)
  3. Journal of Controlled Release (Elsevier Sciences)
  4. Drug Development and Industrial Pharmacy (Marcel & Decker)
  5. International Journal of Pharmaceutics (Elsevier Sciences)


Final Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

Final Year B Pharm Sem VIIBP701T Instrumental Methods of Analysis Theory
BP702T Industrial Pharmacy TheoryBP703T Pharmacy Practice Theory
BP704T Novel Drug Delivery System TheoryBP705 P Instrumental Methods of Analysis Practical
Final Year B Pharm Sem VIIBP801T Biostatistics and Research Methodology Theory
BP802T Social and Preventive Pharmacy TheoryBP803ET Pharmaceutical Marketing Theory
BP804ET Pharmaceutical Regulatory Science TheoryBP805ET Pharmacovigilance Theory
BP806ET Quality Control and Standardization of Herbals TheoryBP807ET Computer-Aided Drug Design Theory
BP808ET Cell and Molecular Biology TheoryBP809ET Cosmetic Science Theory
BP810ET Experimental Pharmacology TheoryBP811ET Advanced Instrumentation Techniques Theory
BP812ET Dietary supplements and NutraceuticalsPharmaceutical Product Development

Suggested readings:


Novel Drug Delivery Systems (NDDS) | Ocular Drug Delivery System