Application of diazotisation titration
Diazotisation titration is a useful analytical method for the determination of primary aromatic amines, which have wide applications in various fields such as dye industry, pharmaceuticals, and agrochemicals. Some of the specific applications of diazotisation titration are as follows:
- Determination of aniline: Diazotisation titration is commonly used for the determination of aniline, which is an important intermediate in the production of dyes, rubber processing chemicals, and pharmaceuticals. Aniline is converted to its diazonium salt using nitrous acid, which is then titrated with a suitable titrant, such as standard iodine solution, to determine the concentration of aniline.
- Determination of nitroanilines: Diazotisation titration can also be used for the determination of nitroanilines, which are used as intermediates in the synthesis of dyes, pigments, and pharmaceuticals. Nitroanilines are first reduced to their corresponding primary aromatic amines, which are then converted to their diazonium salts using nitrous acid and titrated with a suitable titrant.
- Determination of phenols: Diazotisation titration can be used for the determination of phenols, which are used as antioxidants, preservatives, and disinfectants. Phenols are first converted to their corresponding diazonium salts using nitrous acid, which are then titrated with a suitable titrant, such as standard sodium hydroxide solution.
- Determination of primary aromatic amines in food: Diazotisation titration can also be used for the determination of primary aromatic amines in food products, such as cured meats and fish. These products contain nitroso compounds, which are converted to primary aromatic amines using reducing agents and then determined by diazotisation titration.
Overall, diazotisation titration is a useful analytical method for the determination of primary aromatic amines and their derivatives, which have important applications in various industries.
First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise
Suggested readings: