November 14, 2024

Application of diazotisation titration

Application of diazotisation titration

Diazotisation titration is a useful analytical method for the determination of primary aromatic amines, which have wide applications in various fields such as dye industry, pharmaceuticals, and agrochemicals. Some of the specific applications of diazotisation titration are as follows:

  1. Determination of aniline: Diazotisation titration is commonly used for the determination of aniline, which is an important intermediate in the production of dyes, rubber processing chemicals, and pharmaceuticals. Aniline is converted to its diazonium salt using nitrous acid, which is then titrated with a suitable titrant, such as standard iodine solution, to determine the concentration of aniline.
  2. Determination of nitroanilines: Diazotisation titration can also be used for the determination of nitroanilines, which are used as intermediates in the synthesis of dyes, pigments, and pharmaceuticals. Nitroanilines are first reduced to their corresponding primary aromatic amines, which are then converted to their diazonium salts using nitrous acid and titrated with a suitable titrant.
  3. Determination of phenols: Diazotisation titration can be used for the determination of phenols, which are used as antioxidants, preservatives, and disinfectants. Phenols are first converted to their corresponding diazonium salts using nitrous acid, which are then titrated with a suitable titrant, such as standard sodium hydroxide solution.
  4. Determination of primary aromatic amines in food: Diazotisation titration can also be used for the determination of primary aromatic amines in food products, such as cured meats and fish. These products contain nitroso compounds, which are converted to primary aromatic amines using reducing agents and then determined by diazotisation titration.

Overall, diazotisation titration is a useful analytical method for the determination of primary aromatic amines and their derivatives, which have important applications in various industries.

First Year B Pharm Notes, Syllabus, Books, PDF Subjectwise/Topicwise

F Y B Pharm Sem-IF Y B Pharm Sem-II
BP101T Human Anatomy and Physiology I TheoryBP201T Human Anatomy and Physiology II – Theory
BP102T Pharmaceutical Analysis I TheoryBP202T Pharmaceutical Organic Chemistry I Theory
BP103T Pharmaceutics I TheoryBP203T Biochemistry – Theory
BP104T Pharmaceutical Inorganic Chemistry TheoryBP204T Pathophysiology – Theory
BP105T Communication skills TheoryBP205T Computer Applications in Pharmacy Theory
BP106RBT Remedial BiologyBP206T Environmental sciences – Theory
BP106RMT Remedial Mathematics TheoryBP207P Human Anatomy and Physiology II Practical
BP107P Human Anatomy and Physiology PracticalBP208P Pharmaceutical Organic Chemistry I Practical
BP108P Pharmaceutical Analysis I PracticalBP209P Biochemistry Practical
BP109P Pharmaceutics I PracticalBP210P Computer Applications in Pharmacy Practical
BP110P Pharmaceutical Inorganic Chemistry Practical
BP111P Communication skills Practical
BP112RBP Remedial Biology Practical

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